Discovery of the first irreversible small molecule inhibitors of the interaction between the vitamin D receptor and coactivators
about
A natural-product switch for a dynamic protein interfaceHigh-throughput identification of promiscuous inhibitors from screening libraries with the use of a thiol-containing fluorescent probeAnticancer activity of VDR-coregulator inhibitor PS121912.Inhibitors for the Vitamin D Receptor-Coregulator Interaction.Avoiding Fluorescence Assay Interference-The Case for Diaphorase.Antitumor Activity of 3-Indolylmethanamines 31B and PS121912.Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolitesPeroxisome proliferation-activated receptor δ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor.Beyond the ligand-binding pocket: targeting alternate sites in nuclear receptors.Development of novel Vitamin D Receptor-Coactivator InhibitorsSynthesis and evaluation of methylsulfonylnitrobenzamides (MSNBAs) as inhibitors of the thyroid hormone receptor-coactivator interaction.Fluorescence polarization assays in high-throughput screening and drug discovery: a reviewIDENTIFICATION OF VDR ANTAGONISTS AMONG NUCLEAR RECEPTOR LIGANDS USING VIRTUAL SCREENINGModulation of Transcription mediated by the Vitamin D Receptor and the Peroxisome Proliferator-Activated Receptor δ in the presence of GW0742 analogs.Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on the GW0742 Scaffold.Novel VDR antagonists based on the GW0742 scaffold.Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays.A Natural-Product Switch for a Dynamic Protein Interface
P2860
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P2860
Discovery of the first irreversible small molecule inhibitors of the interaction between the vitamin D receptor and coactivators
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Discovery of the first irrever ...... in D receptor and coactivators
@en
Discovery of the first irrever ...... n D receptor and coactivators.
@nl
type
label
Discovery of the first irrever ...... in D receptor and coactivators
@en
Discovery of the first irrever ...... n D receptor and coactivators.
@nl
prefLabel
Discovery of the first irrever ...... in D receptor and coactivators
@en
Discovery of the first irrever ...... n D receptor and coactivators.
@nl
P2093
P2860
P356
P1476
Discovery of the first irrever ...... in D receptor and coactivators
@en
P2093
Athena M Baranowski
Dana Pearson
Daniel D Bikle
Megan M McCallum
Nina Y Yuan
Premchendar Nandhikonda
Tahniyath Ara
Wen Z Lynt
P2860
P304
P356
10.1021/JM300460C
P407
P577
2012-05-16T00:00:00Z