Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1. - Wikidata - awgldk - TriplyDB

Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1.

Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1.

http://www.wikidata.org/entity/Q39363122

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Review of Anti-Inflammatory Herbal Medicines Towards Elucidating Carnosic Acid Biosynthesis in Lamiaceae: Functional Characterization of the Three First Steps of the Pathway in Salvia fruticosa and Rosmarinus officinalis Combined metabolome and transcriptome profiling provides new insights into diterpene biosynthesis in S. pomifera glandular trichomes Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.Nonsteroidal Anti-Inflammatory Therapy: A Journey Toward Safety.Antitumor activity of the dietary diterpene carnosol against a panel of human cancer cell lines.Carnosic acid, a phenolic diterpene from rosemary, prevents UV-induced expression of matrix metalloproteinases in human skin fibroblasts and keratinocytes.Intracellular signaling pathways of inflammation modulated by dietary flavonoids: The most recent evidence.Rosmarinic acid potentiates carnosic acid induced apoptosis in lung fibroblasts.Computational models for the classification of mPGES-1 inhibitors with fingerprint descriptors.Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions.Bioavailability of the major bioactive diterpenoids in a rosemary extract: Metabolic profile in the intestine, liver, plasma, and brain of Zucker rats

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Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1.

http://www.wikidata.org/entity/Q39363122

description

2012 nî lūn-bûn

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Carnosol and carnosic acids fr ...... l prostaglandin E2 synthase-1.

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Carnosol and carnosic acids fr ...... l prostaglandin E2 synthase-1.

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Journal of Pharmacology and Experimental Therapeutics

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Carnosol and carnosic acids fr ...... l prostaglandin E2 synthase-1.

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P2093

Judith M Rollinger

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Julia Bauer

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Olga Scherer

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Susanne Kuehnl

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P2860

Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase

CREB-dependent cyclooxygenase-2 and microsomal prostaglandin E synthase-1 expression is mediated by protein kinase C and calcium

Cyclooxygenases: structural, cellular, and molecular biology

Flavonoid and phenolic glycosides from Salvia officinalis.

Carnosic acid, a rosemary phenolic compound, induces apoptosis through reactive oxygen species-mediated p38 activation in human neuroblastoma IMR-32 cells.

Inhibition of mammalian 5-lipoxygenase and cyclo-oxygenase by flavonoids and phenolic dietary additives. Relationship to antioxidant activity and to iron ion-reducing ability.

Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-kappaB in mouse macrophages.

Anti-inflammatory drugs: new multitarget compounds to face an old problem. The dual inhibition concept.

Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol.

Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1.

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1

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342

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Andreas Koeberle

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2012-04-16T00:00:00Z

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