Probing of C-terminal lysine variation in a recombinant monoclonal antibody production using Chinese hamster ovary cells with chemically defined media.
about
Biochemical Characterization of Human Anti-Hepatitis B Monoclonal Antibody Produced in the Microalgae Phaeodactylum tricornutumHuman IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activationTailoring recombinant protein quality by rational media design.Analysis of Tubespins as a suitable scale-down model of bioreactors for high cell density CHO cell culture.Effect of copper variation in yeast hydrolysate on C-terminal lysine levels of a monoclonal antibody.Cell culture media impact on drug product solution stability.Carboxypeptidase D is the only enzyme responsible for antibody C-terminal lysine cleavage in Chinese hamster ovary (CHO) cells.Impact of cell culture on recombinant monoclonal antibody product heterogeneity.Effects of copper on CHO cells: cellular requirements and product quality considerations.Main Quality Attributes of Monoclonal Antibodies and Effect of Cell Culture ComponentsChemically defined media modifications to lower tryptophan oxidation of biopharmaceuticals.Effect of glycosylation on the partition behavior of a human antibody in aqueous two-phase systems.Insights into the generation of monoclonal antibody acidic charge variants during Chinese hamster ovary cell cultures.Evaluation of heavy chain C-terminal deletions on productivity and product quality of monoclonal antibodies in Chinese hamster ovary (CHO) cells.Risk Mitigation in Preventing Adventitious Agent Contamination of Mammalian Cell Cultures.A Simple Method to Reduce both Lactic Acid and Ammonium Production in Industrial Animal Cell Culture.Effect of cell culture medium components on color of formulated monoclonal antibody drug substance.Combination of temperature shift and hydrolysate addition regulates anti-IgE monoclonal antibody charge heterogeneity in Chinese hamster ovary cell fed-batch culture.Elucidating the effects of arginine and lysine on a monoclonal antibody C-terminal lysine variation in CHO cell cultures.Modulation of mAb quality attributes using microliter scale fed-batch cultures.
P2860
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P2860
Probing of C-terminal lysine variation in a recombinant monoclonal antibody production using Chinese hamster ovary cells with chemically defined media.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Probing of C-terminal lysine v ...... with chemically defined media.
@en
Probing of C-terminal lysine v ...... with chemically defined media.
@nl
type
label
Probing of C-terminal lysine v ...... with chemically defined media.
@en
Probing of C-terminal lysine v ...... with chemically defined media.
@nl
prefLabel
Probing of C-terminal lysine v ...... with chemically defined media.
@en
Probing of C-terminal lysine v ...... with chemically defined media.
@nl
P2093
P2860
P356
P1476
Probing of C-terminal lysine v ...... with chemically defined media.
@en
P2093
Ashraf Amanullah
Jian Zhang
Terry Hudson
Wen-Lin Tsai
P2860
P304
P356
10.1002/BIT.24510
P577
2012-04-11T00:00:00Z