Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis - Wikidata - awgldk - TriplyDB

Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis

Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis

http://www.wikidata.org/entity/Q39386624

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Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP Inhibitory signalling to the Arp2/3 complex steers cell migration Unravelling the Actin Cytoskeleton: A New Competitive Edge?Rho GTPase signalling in cell migration At the leading edge of three-dimensional cell migration Dynamic reorganization of the actin cytoskeleton Cell type-dependent mechanisms for formin-mediated assembly of filopodia.CARMIL2 is a novel molecular connection between vimentin and actin essential for cell migration and invadopodia formation Migration of T cells on surfaces containing complex nanotopography α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.Protrusive waves guide 3D cell migration along nanofibers.GMFβ controls branched actin content and lamellipodial retraction in fibroblasts.WIP regulates persistence of cell migration and ruffle formation in both mesenchymal and amoeboid modes of motility Profilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and -independent pathways.Mesenchymal chemotaxis requires selective inactivation of myosin II at the leading edge via a noncanonical PLCγ/PKCα pathway.Visualization of phosphatidic acid fluctuations in the plasma membrane of living cells Functional hierarchy of redundant actin assembly factors revealed by fine-grained registration of intrinsic image fluctuations.Arp2/3 inhibition induces amoeboid-like protrusions in MCF10A epithelial cells by reduced cytoskeletal-membrane coupling and focal adhesion assembly Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion ERK reinforces actin polymerization to power persistent edge protrusion during motility.Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin Functions of nonmuscle myosin II in assembly of the cellular contractile system Cell Migration and Invadopodia Formation Require a Membrane-binding Domain of CARMIL2.Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration.The Role of Rac1 in the Growth Cone Dynamics and Force Generation of DRG Neurons The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology Capping protein is essential for cell migration in vivo and for filopodial morphology and dynamics.PAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth.Micro total analysis systems: fundamental advances and applications in the laboratory, clinic, and field.How actin network dynamics control the onset of actin-based motility.CD2AP links cortactin and capping protein at the cell periphery to facilitate formation of lamellipodia.SCAR/WAVE-mediated processing of engulfed apoptotic corpses is essential for effective macrophage migration in Drosophila Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin.Physiological role of the interaction between CARMIL1 and capping protein.Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation.Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo.Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells.Mechanisms of leading edge protrusion in interstitial migration.

P2860

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P2860

Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis

http://www.wikidata.org/entity/Q39386624

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

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2012年學術文章

@zh-hant

name

Arp2/3 is critical for lamelli ...... is dispensable for chemotaxis

@en

Arp2/3 is critical for lamelli ...... is dispensable for chemotaxis.

@nl

type

label

Arp2/3 is critical for lamelli ...... is dispensable for chemotaxis

@en

Arp2/3 is critical for lamelli ...... is dispensable for chemotaxis.

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prefLabel

Arp2/3 is critical for lamelli ...... is dispensable for chemotaxis

@en

Arp2/3 is critical for lamelli ...... is dispensable for chemotaxis.

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J.CELL.2011.12.034

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P1476

Arp2/3 is critical for lamelli ...... is dispensable for chemotaxis

@en

P2093

Congying Wu

http://www.w3.org/2001/XMLSchema#string

Elizabeth M Haynes

http://www.w3.org/2001/XMLSchema#string

Jack D Griffith

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James E Bear

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Matthew E Berginski

http://www.w3.org/2001/XMLSchema#string

Shawn M Gomez

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Sreeja B Asokan

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P2860

Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge

Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia.

Cellular and molecular mechanisms of fibrosis

The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia

High-resolution quantification of focal adhesion spatiotemporal dynamics in living cells

Characterization of two classes of small molecule inhibitors of Arp2/3 complex

Cellular motility driven by assembly and disassembly of actin filaments

Actin, a central player in cell shape and movement

The ARP2/3 complex: an actin nucleator comes of age

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5

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148

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Norman Sharpless

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2012-03-01T00:00:00Z

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221884375

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22385962

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extracellular matrix

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3707508

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