Outgrowth of single oncogene-expressing cells from suppressive epithelial environments.
about
In vitro models of the metastatic cascade: from local invasion to extravasationPar6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers.A protein interaction map for cell-cell adhesion regulators identifies DUSP23 as a novel phosphatase for β-catenin.A PAK6-IQGAP1 complex promotes disassembly of cell-cell adhesionsSuppression and activation of the malignant phenotype by extracellular matrix in xenograft models of bladder cancer: a model for tumor cell "dormancy"Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence"Tightly controlled MRTF-A activity regulates epithelial differentiation during formation of mammary acini.Luminal mitosis drives epithelial cell dispersal within the branching ureteric budAutophagy in oncogenic K-Ras promotes basal extrusion of epithelial cells by degrading S1P'Particle genetics': treating every cell as unique.Oncogenic transformation of diverse gastrointestinal tissues in primary organoid cultureTrafficking of epidermal growth factor receptor ligands in polarized epithelial cells.Epithelial junctions maintain tissue architecture by directing planar spindle orientation.The invadopodia scaffold protein Tks5 is required for the growth of human breast cancer cells in vitro and in vivo.The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapiesResolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.Three-dimensional organotypic culture: experimental models of mammalian biology and disease.Active contractility at E-cadherin junctions and its implications for cell extrusion in cancerThree-dimensional modeling of ovarian cancer.The cell competition-based high-throughput screening identifies small compounds that promote the elimination of RasV12-transformed cells from epithelia.Development and characterization of salivary adenoid cystic carcinoma cell line.Programmed synthesis of three-dimensional tissues.Epithelial Tumors Originate in Tumor Hotspots, a Tissue-Intrinsic Microenvironment.Overexpression and β-1,6-N-acetylglucosaminylation-initiated aberrant glycosylation of TIMP-1: a "double whammy" strategy in colon cancer progressionHeat shock factor Hsf1 cooperates with ErbB2 (Her2/Neu) protein to promote mammary tumorigenesis and metastasis.Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectivesDirecting the assembly of spatially organized multicomponent tissues from the bottom up.Host epithelial geometry regulates breast cancer cell invasiveness.Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERKProgrammed cell-to-cell variability in Ras activity triggers emergent behaviors during mammary epithelial morphogenesis.Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheresBreaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4How integrins control breast biology.Both the anti- and pro-apoptotic functions of villin regulate cell turnover and intestinal homeostasis.PTEN phosphatase-independent maintenance of glandular morphology in a predictive colorectal cancer model system.Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids.Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells.Dissecting social cell biology and tumors using Drosophila genetics.
P2860
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P2860
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments.
@en
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments.
@nl
type
label
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments.
@en
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments.
@nl
prefLabel
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments.
@en
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments.
@nl
P2860
P356
P1433
P1476
Outgrowth of single oncogene-expressing cells from suppressive epithelial environments
@en
P2093
Joan S Brugge
P2860
P2888
P304
P356
10.1038/NATURE10826
P407
P577
2012-02-08T00:00:00Z
P5875
P6179
1001850722