Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK
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Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fateAutophagy in malignant transformation and cancer progressionMechanisms of disseminated cancer cell dormancy: an awakening fieldInterplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapyHepatoprotective role of Sestrin2 against chronic ER stressIκB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathwayROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway.Stress signaling and the shaping of the mammary tissue in development and cancer.NDRG2 overexpression enhances glucose deprivation-mediated apoptosis in breast cancer cells via inhibition of the LKB1-AMPK pathway.ERK-regulated αB-crystallin induction by matrix detachment inhibits anoikis and promotes lung metastasis in vivo.DAP1, a negative regulator of autophagy, controls SubAB-mediated apoptosis and autophagy.Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells.PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2's mitochondria translocation.The role of multicellular aggregation in the survival of ErbB2-positive breast cancer cells during extracellular matrix detachmentIntact LKB1 activity is required for survival of dormant ovarian cancer spheroidsER stress: Autophagy induction, inhibition and selection.Functional role of autophagy in gastric cancer.Protective effect of mild endoplasmic reticulum stress on radiation-induced bystander effects in hepatocyte cells.Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer.Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming.Insulin-like growth factor 1 receptor-mediated cell survival in hypoxia depends on the promotion of autophagy via suppression of the PI3K/Akt/mTOR signaling pathway.Molecular pathways: the PERKs and pitfalls of targeting the unfolded protein response in cancer.Integrating autophagy and metabolism in cancer.Stress management by autophagy: Implications for chemoresistance.mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines.Molecular Functions of Glycoconjugates in Autophagy.Autophagy in cancer metastasis.Autophagy and epithelial-mesenchymal transition: an intricate interplay in cancer.The Interconnections between Autophagy and Integrin-Mediated Cell Adhesion.Protein disulfide isomerases in the endoplasmic reticulum promote anchorage-independent growth of breast cancer cells.A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival.The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer.Detachment-Based Equilibrium of Anoikic Cell Death and Autophagic Cell Survival Through Adaptor Protein p66(Shc).Functional significance of co-occurring mutations in PIK3CA and MAP3K1 in breast cancer.
P2860
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P2860
Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Regulation of autophagy during ...... e inhibition of mTORC1 by PERK
@ast
Regulation of autophagy during ...... e inhibition of mTORC1 by PERK
@en
type
label
Regulation of autophagy during ...... e inhibition of mTORC1 by PERK
@ast
Regulation of autophagy during ...... e inhibition of mTORC1 by PERK
@en
prefLabel
Regulation of autophagy during ...... e inhibition of mTORC1 by PERK
@ast
Regulation of autophagy during ...... e inhibition of mTORC1 by PERK
@en
P2093
P2860
P356
P1433
P1476
Regulation of autophagy during ...... e inhibition of mTORC1 by PERK
@en
P2093
A Avivar-Valderas
E Bobrovnikova-Marjon
J Alan Diehl
N Bardeesy
P2860
P2888
P304
P356
10.1038/ONC.2012.512
P407
P577
2012-11-19T00:00:00Z