Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.
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Trans-ethnic meta-analysis identifies common and rare variants associated with hepatocyte growth factor levels in the Multi-Ethnic Study of Atherosclerosis (MESA).Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and LipogenesisCancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer.Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells.FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and GPerinatal exposure of mice to the pesticide DDT impairs energy expenditure and metabolism in adult female offspring.Up-regulated FASN expression promotes transcoelomic metastasis of ovarian cancer cell through epithelial-mesenchymal transitionProfiling of serum metabolites in canine lymphoma using gas chromatography mass spectrometryActivation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model.Signalling mechanisms regulating phenotypic changes in breast cancer cells.Nuclear expression of Lyn, a Src family kinase member, is associated with poor prognosis in renal cancer patients.Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression.Metformin-induced killing of triple-negative breast cancer cells is mediated by reduction in fatty acid synthase via miRNA-193bDownregulation of Plasma MiR-142-3p and MiR-26a-5p in Patients With Colorectal Carcinoma.The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathwaysOverexpression of fatty acid synthase predicts a poor prognosis for human gastric cancerStalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance.NMU signaling promotes endometrial cancer cell progression by modulating adhesion signaling.Liver fatty acid-binding protein (L-Fabp) modifies intestinal fatty acid composition and adenoma formation in ApcMin/+ mice.The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cells.Anti-Metastatic and Anti-Angiogenic Activities of Core-Shell SiO2@LDH Loaded with Etoposide in Non-Small Cell Lung Cancer.miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer and lung cancer.Fatty acid synthase mediates the epithelial-mesenchymal transition of breast cancer cells.Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer.Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer.Brain metastases from colorectal cancer: microenvironment and molecular mechanisms.Metabolic implication of tumor:stroma crosstalk in breast cancer.ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer.Development of Halofluorochromic Polymer Nanoassemblies for the Potential Detection of Liver Metastatic Colorectal Cancer Tumors Using Experimental and Computational Approaches.Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism.Increased HAGLR expression promotes non-small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis.Inhibition of fatty acid synthase suppresses neovascularization via regulating the expression of VEGF-A in glioma.Lipid desaturation - the next step in targeting lipogenesis in cancer?Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respirationRecent advances in targeting the fatty acid biosynthetic pathway using fatty acid synthase inhibitors.MicroRNA-142-3p, a novel target of tumor suppressor menin, inhibits osteosarcoma cell proliferation by down-regulation of FASN.Elevated expression of fatty acid synthase and nuclear localization of carnitine palmitoyltransferase 1C are common among human gliomas.Metformin treatment reduces temozolomide resistance of glioblastoma cells.RETRACTED ARTICLE: Casticin inhibits epithelial-mesenchymal transition of EBV-infected human retina pigmental epithelial cells through the modulation of intracellular lipogenesis.Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo
P2860
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P2860
Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Inhibition of fatty acid synth ...... tastasis in colorectal cancer.
@en
Inhibition of fatty acid synth ...... tastasis in colorectal cancer.
@nl
type
label
Inhibition of fatty acid synth ...... tastasis in colorectal cancer.
@en
Inhibition of fatty acid synth ...... tastasis in colorectal cancer.
@nl
prefLabel
Inhibition of fatty acid synth ...... tastasis in colorectal cancer.
@en
Inhibition of fatty acid synth ...... tastasis in colorectal cancer.
@nl
P2093
P2860
P50
P1433
P1476
Inhibition of fatty acid synth ...... tastasis in colorectal cancer.
@en
P2093
Andrew J Morris
B Mark Evers
Heidi L Weiss
Pat Gulhati
Victoria A Elliott
William C Mustain
Yekaterina Y Zaytseva
P2860
P304
P356
10.1158/0008-5472.CAN-11-4057
P407
P577
2012-01-19T00:00:00Z