Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.
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Is cancer a metabolic disease?Alternative fuels for cancer cellsRole of oxidative stress and the microenvironment in breast cancer development and progressionTumor suppressor p53 and its mutants in cancer metabolismTwo-way communication between the metabolic and cell cycle machineries: the molecular basisOn metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancerReexamining cancer metabolism: Lactate production for carcinogenesis could be the purpose and explanation of the Warburg effectHypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symportersPCK2 activation mediates an adaptive response to glucose depletion in lung cancerElucidation of how cancer cells avoid acidosis through comparative transcriptomic data analysis.Evaluation of MCT1, MCT4 and CD147 Genes in Peripheral Blood Cells of Breast Cancer Patients and Their Potential Use as Diagnostic and Prognostic Markers.Cancer heterogeneity is not compatible with one unique cancer cell metabolic mapRegulation of pyruvate metabolism and human diseaseMonocarboxylate transporters 1-4 in NSCLC: MCT1 is an independent prognostic marker for survivalCell surface lactate receptor GPR81 is crucial for cancer cell survival.A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling.Restricting carbohydrates to fight head and neck cancer-is this realistic?Epithelial cell proliferation arrest induced by lactate and acetate from Lactobacillus casei and Bifidobacterium breveCatabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.Spatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation.Mesenchymal Stem/Stromal Cells under Stress Increase Osteosarcoma Migration and Apoptosis Resistance via Extracellular Vesicle Mediated Communication.Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation.Metabolic regulation of oxygen and redox homeostasis by p53: lessons from evolutionary biology?Mitochondrial Metabolism as a Treatment Target in Anaplastic Thyroid Cancer.Role of PI3K-AKT-mTOR and Wnt Signaling Pathways in Transition of G1-S Phase of Cell Cycle in Cancer Cells.ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer.BAY11 enhances OCT4 synthetic mRNA expression in adult human skin cells.Monocarboxylate transporters in the brain and in cancer.Metabolic regulation by p53 family members.Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer.Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours.CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells.Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas.The Promotion of Erythropoiesis via the Regulation of Reactive Oxygen Species by Lactic Acid.Regulation of glycolysis in head and neck squamous cell carcinoma.Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force.Targeting lactate metabolism for cancer therapeutics.Regulation of Cellular Metabolism and Hypoxia by p53.The Role of pH Regulation in Cancer Progression.The p53 family orchestrates the regulation of metabolism: physiological regulation and implications for cancer therapy.
P2860
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P2860
Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Regulation of monocarboxylate ...... ward lactate fluxes in tumors.
@en
Regulation of monocarboxylate ...... ward lactate fluxes in tumors.
@nl
type
label
Regulation of monocarboxylate ...... ward lactate fluxes in tumors.
@en
Regulation of monocarboxylate ...... ward lactate fluxes in tumors.
@nl
prefLabel
Regulation of monocarboxylate ...... ward lactate fluxes in tumors.
@en
Regulation of monocarboxylate ...... ward lactate fluxes in tumors.
@nl
P2093
P1433
P1476
Regulation of monocarboxylate ...... tward lactate fluxes in tumors
@en
P2093
Aline Meulle
Aude Le Breton
Chantal Dessy
Olivier Feron
Romain Boidot
Sarab Lizard-Nacol
P304
P356
10.1158/0008-5472.CAN-11-2474
P407
P577
2011-12-19T00:00:00Z