Reduced drug uptake in phenotypically resistant nutrient-starved nonreplicating Mycobacterium tuberculosis.
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Stochastic expression of a multiple antibiotic resistance activator confers transient resistance in single cellsWhat can we offer to 3 million MDRTB household contacts in 2016?Mycobacterium tuberculosis Transcription Machinery: Ready To Respond to Host AttacksFirst-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosisRifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation modelThe path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells.Expression of antimicrobial drug tolerance by attached communities of Mycobacterium tuberculosis.UDP-N-acetylmuramic acid l-alanine ligase (MurC) inhibition in a tolC mutant Escherichia coli strain leads to cell deathDeficiency of the novel exopolyphosphatase Rv1026/PPX2 leads to metabolic downshift and altered cell wall permeability in Mycobacterium tuberculosisImperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance.Ribosome hibernation facilitates tolerance of stationary-phase bacteria to aminoglycosidesUsing Chemical Reaction Kinetics to Predict Optimal Antibiotic Treatment Strategies.Eagle Effect in Nonreplicating Persister MycobacteriaA High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis.Boromycin Kills Mycobacterial Persisters without Detectable ResistanceMultiscale Model of Mycobacterium tuberculosis Infection Maps Metabolite and Gene Perturbations to Granuloma Sterilization PredictionsMild Nutrient Starvation Triggers the Development of a Small-Cell Survival Morphotype in Mycobacteria.A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesisDisruption of Membrane by Colistin Kills Uropathogenic Escherichia coli Persisters and Enhances Killing of Other AntibioticsProduction of Superoxide in Bacteria Is Stress- and Cell State-Dependent: A Gating-Optimized Flow Cytometry Method that Minimizes ROS Measurement Artifacts with Fluorescent Dyes.The normalcy of dormancy: common themes in microbial quiescencePersisters, persistent infections and the Yin-Yang model.Membrane-targeting AM-0016 kills mycobacterial persisters and shows low propensity for resistance development.Targeting Phenotypically Tolerant Mycobacterium tuberculosis.Kunkel Lecture: Fundamental immunodeficiency and its correction.Inhibition of IL-17A by secukinumab shows no evidence of increased Mycobacterium tuberculosis infections.NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans.Activity of lipophilic and hydrophilic drugs against dormant and replicating Mycobacterium tuberculosis.A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis.Improved efficacy of fosmidomycin against Plasmodium and Mycobacterium species by combination with the cell-penetrating peptide octaarginine.Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis.Hit Generation in TB Drug Discovery: From Genome to Granuloma.Verapamil targets membrane energetics in Mycobacterium tuberculosis.Drug targets in dormant Mycobacterium tuberculosis: can the conquest against tuberculosis become a reality?NTM drug discovery: status, gaps and the way forward.Targeting the Proteostasis Network for Mycobacterial Drug Discovery.Mycobacterial Response to Organic Solvents and Possible Implications on Cross-Resistance With Antimicrobial Agents.Superoxide dismutase activity confers (p)ppGpp-mediated antibiotic tolerance to stationary-phase
P2860
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P2860
Reduced drug uptake in phenotypically resistant nutrient-starved nonreplicating Mycobacterium tuberculosis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
@zh-hant
name
Reduced drug uptake in phenoty ...... ng Mycobacterium tuberculosis.
@en
Reduced drug uptake in phenoty ...... ng Mycobacterium tuberculosis.
@nl
type
label
Reduced drug uptake in phenoty ...... ng Mycobacterium tuberculosis.
@en
Reduced drug uptake in phenoty ...... ng Mycobacterium tuberculosis.
@nl
prefLabel
Reduced drug uptake in phenoty ...... ng Mycobacterium tuberculosis.
@en
Reduced drug uptake in phenoty ...... ng Mycobacterium tuberculosis.
@nl
P2860
P356
P1476
Reduced drug uptake in phenoty ...... ng Mycobacterium tuberculosis.
@en
P2093
Jansy Sarathy
Véronique Dartois
P2860
P304
P356
10.1128/AAC.02202-12
P407
P577
2013-01-18T00:00:00Z