CPTH6, a thiazole derivative, induces histone hypoacetylation and apoptosis in human leukemia cells.
about
The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic targetKATs in cancer: functions and therapiesHistone acetyltransferase inhibitors block neuroblastoma cell growth in vivoHistone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer.A novel benzothiazole derivative YLT322 induces apoptosis via the mitochondrial apoptosis pathway in vitro with anti-tumor activity in solid malignancies.Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth.The thiazole derivative CPTH6 impairs autophagyAffinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein.Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells.Novel thiazole derivatives: a patent review (2008 - 2012; Part 1).tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells.KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2.Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.Quinoline-Based p300 Histone Acetyltransferase Inhibitors with Pro-apoptotic Activity in Human Leukemia U937 Cells
P2860
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P2860
CPTH6, a thiazole derivative, induces histone hypoacetylation and apoptosis in human leukemia cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
CPTH6, a thiazole derivative, ...... tosis in human leukemia cells.
@en
CPTH6, a thiazole derivative, ...... tosis in human leukemia cells.
@nl
type
label
CPTH6, a thiazole derivative, ...... tosis in human leukemia cells.
@en
CPTH6, a thiazole derivative, ...... tosis in human leukemia cells.
@nl
prefLabel
CPTH6, a thiazole derivative, ...... tosis in human leukemia cells.
@en
CPTH6, a thiazole derivative, ...... tosis in human leukemia cells.
@nl
P2093
P50
P1476
CPTH6, a thiazole derivative, ...... ptosis in human leukemia cells
@en
P2093
Adriana Bolasco
Giovanna Maresca
Ylenia Ragazzoni
P304
P356
10.1158/1078-0432.CCR-11-0579
P407
P50
P577
2011-11-08T00:00:00Z