Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.
about
Valsartan independent of AT₁ receptor inhibits tissue factor, TLR-2 and -4 expression by regulation of Egr-1 through activation of AMPK in diabetic conditions.Macrophage-derived IL-6 contributes to ANG II-mediated angiotensinogen stimulation in renal proximal tubular cells.Angiotensin type 1a receptor-deficient mice develop diabetes-induced cardiac dysfunction, which is prevented by renin-angiotensin system inhibitors.The adipose tissue renin-angiotensin system and metabolic disorders: a review of molecular mechanisms.The endocrinology of food intake.Direct renin inhibition prevents cardiac dysfunction in a diabetic mouse model: comparison with an angiotensin receptor antagonist and angiotensin-converting enzyme inhibitorDPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice.Nitric oxide synthesis-promoting effects of valsartan in human umbilical vein endothelial cells via the Akt/adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathwayValsartan ameliorates the constitutive adipokine expression pattern in mature adipocytes: a role for inverse agonism of the angiotensin II type 1 receptor in obesity.
P2860
Q34571546-1CBD7123-E0E9-47C6-B353-D9E9A237B572Q37172306-B5B7C2BE-568C-48B3-BDC1-0FCE7E755B15Q37314939-ADBB9B62-8E1B-47FA-AF50-31053D9C140CQ38020530-C79CF627-6AA5-484B-AECD-93E22CCCB567Q38123372-BB6E18ED-9A8C-4ACC-ADC0-6997FF34BA59Q38691518-E30F8956-99FE-4A28-B931-60801FB76F80Q38870486-D9891C2F-9DA0-4F40-BA9D-77D71401CB9FQ40928856-D5B5A34F-3D0E-4D6E-A4A4-40C50CD8A59BQ42198231-E2450BD3-2F2D-4F44-B964-C4DF9B1A9F79Q42805768-663B8318-7CA4-482D-ACAB-4AAB3B38D393
P2860
Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
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2011年學術文章
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name
Valsartan, independently of AT ...... ance in cocultured adipocytes.
@en
Valsartan, independently of AT ...... ance in cocultured adipocytes.
@nl
type
label
Valsartan, independently of AT ...... ance in cocultured adipocytes.
@en
Valsartan, independently of AT ...... ance in cocultured adipocytes.
@nl
prefLabel
Valsartan, independently of AT ...... ance in cocultured adipocytes.
@en
Valsartan, independently of AT ...... ance in cocultured adipocytes.
@nl
P2093
P2860
P1476
Valsartan, independently of AT ...... ance in cocultured adipocytes.
@en
P2093
Fusanori Nishimura
Haruya Ohno
Hideaki Kamata
Hideyuki Sakoda
Hiroki Kurihara
Hiroshi Akazawa
Midori Fujishiro
Misaki Iwashita
Sonoko Kumamoto
Takako Kikuchi
P2860
P304
P356
10.1152/AJPENDO.00324.2011
P577
2011-11-01T00:00:00Z