NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling. - Wikidata - awgldk - TriplyDB

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.

http://www.wikidata.org/entity/Q39459534

about

Biological activity of lenalidomide and its underlying therapeutic effects in multiple myeloma S-nitrosylation of FLICE inhibitory protein determines its interaction with RIP1 and activation of NF-kappa B TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8 A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells.An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1 Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria Chemoresistance in human ovarian cancer: the role of apoptotic regulators Surface TRAIL decoy receptor-4 expression is correlated with TRAIL resistance in MCF7 breast cancer cells The two faces of receptor interacting protein kinase-1 Programmed necrosis in the cross talk of cell death and inflammation Elevation of c-FLIP in castrate-resistant prostate cancer antagonizes therapeutic response to androgen receptor-targeted therapy To NFκB or not to NFκB: The Dilemma on How to Inhibit a Cancer Cell Fate Regulator Cell death and autophagy in tuberculosis FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis The heme oxygenase-1 and c-FLIP in acute myeloid leukemias: two non-redundant but mutually exclusive cellular safeguards protecting cells against TNF-induced cell death?Computational modelling of LY303511 and TRAIL-induced apoptosis suggests dynamic regulation of cFLIP ON/OFF and beyond--a boolean model of apoptosis Mathematical modelling of cell-fate decision in response to death receptor engagement Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus Modulating cell-to-cell variability and sensitivity to death ligands by co-drugging.Oxidative stress sensitizes bladder cancer cells to TRAIL mediated apoptosis by down-regulating anti-apoptotic proteins Herpes simplex virus type 1 (HSV-1)-induced apoptosis in human dendritic cells as a result of downregulation of cellular FLICE-inhibitory protein and reduced expression of HSV-1 antiapoptotic latency-associated transcript sequences.Escape of HIV-1-infected dendritic cells from TRAIL-mediated NK cell cytotoxicity during NK-DC cross-talk--a pivotal role of HMGB1.Increased radiosensitivity and radiation-induced apoptosis in SRC-3 knockout mice.The need for a standard nomenclature for gene classification (a Nucleotide Function Code) and an automated data-based tool to assist in understanding the molecular associations in cell signalling in plant-pathogen interactions.Transcription factor NF-kappaB differentially regulates death receptor 5 expression involving histone deacetylase 1.Neuronal I kappa B kinase beta protects mice from autoimmune encephalomyelitis by mediating neuroprotective and immunosuppressive effects in the central nervous system.Caspase inhibition sensitizes inhibitor of NF-kappaB kinase beta-deficient fibroblasts to caspase-independent cell death via the generation of reactive oxygen species.Rocaglamide sensitizes leukemic T cells to activation-induced cell death by differential regulation of CD95L and c-FLIP expression.Expression of cellular FLICE inhibitory proteins (cFLIP) in normal and traumatic murine and human cerebral cortex TNF-alpha-induced mitochondrial alterations in human T cells requires FADD and caspase-8 activation but not RIP and caspase-3 activation c-Fos as a proapoptotic agent in TRAIL-induced apoptosis in prostate cancer cells

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P2860

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.

http://www.wikidata.org/entity/Q39459534

description

2001 nî lūn-bûn

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2001年の論文

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2001年論文

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2001年論文

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2001年论文

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2001年论文

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name

NF-kappaB inducers upregulate ...... r of death receptor signaling.

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NF-kappaB inducers upregulate ...... r of death receptor signaling.

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NF-kappaB inducers upregulate ...... r of death receptor signaling.

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NF-kappaB inducers upregulate ...... r of death receptor signaling.

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NF-kappaB inducers upregulate ...... r of death receptor signaling.

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MCB.21.12.3964-3973.2001

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Molecular and Cellular Biology

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NF-kappaB inducers upregulate ...... r of death receptor signaling.

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D Siegmund

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P Scheurich

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S Kreuz

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P2860

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

Inhibition of death receptor signals by cellular FLIP

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death

Transdominant mutants of I kappa B alpha block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation

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3964-3973

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10.1128/MCB.21.12.3964-3973.2001

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