Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.
about
Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasionThe Contrived Mutant p53 Oncogene - Beyond Loss of FunctionsMutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion.MiR-766 induces p53 accumulation and G2/M arrest by directly targeting MDM4.Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas.Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cellsComprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemiap53 Represses the Oncogenic Sno-MiR-28 Derived from a SnoRNAMutant p53: one name, many proteins.Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processingERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function.The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins.TP53 mutants in the tower of babel of cancer progression.Mutant p53 in cancer: new functions and therapeutic opportunities.New insight on the biological role of p53 protein as a tumor suppressor: re-evaluation of its clinical significance in triple-negative breast cancer.p53 regulates cytoskeleton remodeling to suppress tumor progression.Mutant p53 upregulates alpha-1 antitrypsin expression and promotes invasion in lung cancer.Functions of TAp63 and p53 in restraining the development of metastatic cancer.Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretomep53-R273H upregulates neuropilin-2 to promote cell mobility and tumor metastasisMutant p53 stimulates cell invasion through an interaction with Rad21 in human ovarian cancer cells.Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation.Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others.Li-Fraumeni Syndrome Disease Model: A Platform to Develop Precision Cancer Therapy Targeting Oncogenic p53.Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis.
P2860
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P2860
Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Mutant p53 drives multinucleat ...... that is suppressed by ANKRD11.
@en
Mutant p53 drives multinucleat ...... that is suppressed by ANKRD11.
@nl
type
label
Mutant p53 drives multinucleat ...... that is suppressed by ANKRD11.
@en
Mutant p53 drives multinucleat ...... that is suppressed by ANKRD11.
@nl
prefLabel
Mutant p53 drives multinucleat ...... that is suppressed by ANKRD11.
@en
Mutant p53 drives multinucleat ...... that is suppressed by ANKRD11.
@nl
P2093
P2860
P50
P356
P1433
P1476
Mutant p53 drives multinucleat ...... that is suppressed by ANKRD11
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2011.456
P407
P577
2011-10-10T00:00:00Z