about
Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion.The oncogenic role of miR-155 in breast cancer.Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex.Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cellsDevelopment of a novel cell-based assay system EPISSAY for screening epigenetic drugs and liposome formulated decitabine.p53 Represses the Oncogenic Sno-MiR-28 Derived from a SnoRNAWild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9TAp63 regulates oncogenic miR-155 to mediate migration and tumour growth.The application of delivery systems for DNA methyltransferase inhibitors.Ankrd11 is a chromatin regulator involved in autism that is essential for neural development.Mutant p53 upregulates alpha-1 antitrypsin expression and promotes invasion in lung cancer.Characterization of ANKRD11 mutations in humans and mice related to KBG syndrome.Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling.A template-based approach to inhibitors of calpain 2, 20S proteasome, and HIV-1 protease.Ankrd11 is a chromatin regulator involved in autism that is essential for neural development.Pre-activation of the p53 pathway through Nutlin-3a sensitises sarcomas to drozitumab therapy.Specific-site methylation of tumour suppressor ANKRD11 in breast cancer.Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretomeMutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.Genome-wide mapping of ZNF652 promoter binding sites in breast cancer cells.Nutlin-3a is a potential therapeutic for ewing sarcoma.CBFA2T3-ZNF651, like CBFA2T3-ZNF652, functions as a transcriptional corepressor complex.Identification of ANKRD11 as a p53 coactivator.Targeting the p53 Pathway in Ewing Sarcoma.Stimulating p53 down-under: a report from the 1st Australian p53 Workshop.Systematic characterisation of the rat and human CYP24A1 promoter.New 26S proteasome inhibitors with high selectivity for chymotrypsin-like activity and p53-dependent cytotoxicity.Synthesis and extended activity of triazole-containing macrocyclic protease inhibitors.CBFA2T3-ZNF652 corepressor complex regulates transcription of the E-box gene HEB.A comparison of vitamin D activity in paired non-malignant and malignant human breast tissues.
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Paul M Neilsen
@ast
Paul M Neilsen
@en
Paul M Neilsen
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Paul M Neilsen
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Paul M Neilsen
@sl
type
label
Paul M Neilsen
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Paul M Neilsen
@en
Paul M Neilsen
@es
Paul M Neilsen
@nl
Paul M Neilsen
@sl
prefLabel
Paul M Neilsen
@ast
Paul M Neilsen
@en
Paul M Neilsen
@es
Paul M Neilsen
@nl
Paul M Neilsen
@sl
P106
P21
P31
P496
0000-0001-7937-3675