Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas - Wikidata - awgldk - TriplyDB

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

http://www.wikidata.org/entity/Q39472160

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The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma Osteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted Therapies Common stemness regulators of embryonic and cancer stem cells The role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lung Aldh1 Expression and Activity Increase During Tumor Evolution in Sarcoma Cancer Stem Cell Populations.FOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathways SOX2 is required to maintain cancer stem cells in ovarian cancer.YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells Inactivation of p38 MAPK contributes to stem cell-like properties of non-small cell lung cancer Oncopig Soft-Tissue Sarcomas Recapitulate Key Transcriptional Features of Human Sarcomas SOX2 enhances the migration and invasion of ovarian cancer cells via Src kinase Emerging role of long non-coding RNA SOX2OT in SOX2 regulation in breast cancer SOX2 expression is regulated by BRAF and contributes to poor patient prognosis in colorectal cancer Sox2 promotes malignancy in glioblastoma by regulating plasticity and astrocytic differentiation Characterization of cancer stem-like cells derived from mouse induced pluripotent stem cells transformed by tumor-derived extracellular vesicles.Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells.SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells.Silencing SOX2 induced mesenchymal-epithelial transition and its expression predicts liver and lymph node metastasis of CRC patients.Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays miR-382 inhibits osteosarcoma metastasis and relapse by targeting Y box-binding protein 1.Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2.Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure.Roles of sex-determining region Y-box 2 in cell pluripotency and tumor-related signaling pathways.Inhibition of SOX2 induces cell apoptosis and G1/S arrest in Ewing's sarcoma through the PI3K/Akt pathway Downregulation of YAP-dependent Nupr1 promotes tumor-repopulating cell growth in soft matrices.Osteosarcoma: mouse models, cell of origin and cancer stem cell SOX2 regulates YAP1 to maintain stemness and determine cell fate in the osteo-adipo lineage.SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells The multiple roles for Sox2 in stem cell maintenance and tumorigenesis.Defective autophagy leads to the suppression of stem-like features of CD271+ osteosarcoma cells.miR-126 functions as a tumor suppressor in osteosarcoma by targeting Sox2.PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity.SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis.microRNA-625 inhibits tumorigenicity by suppressing proliferation, migration and invasion in malignant melanoma.FOXC2 augments tumor propagation and metastasis in osteosarcoma.Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells.Perspectives on cancer stem cells in osteosarcoma SOX2 and cancer: current research and its implications in the clinic

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Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

http://www.wikidata.org/entity/Q39472160

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

@en

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas.

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type

label

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

@en

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas.

@nl

prefLabel

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

@en

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas.

@nl

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Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

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A Mansukhani

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C Basilico

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E Seo

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J A Perry

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L Ramanathapuram

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S H Orkin

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T B Rapp

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P2860

Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression

Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors

Wnt/beta-catenin signaling in development and disease

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3

Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice

Multipotent cell lineages in early mouse development depend on SOX2 function

Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation

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10.1038/ONC.2011.405

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