Activation of pancreatic zymogens. Normal activation, premature intrapancreatic activation, protective mechanisms against inappropriate activation.
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Hereditary pancreatitis: new insights into acute and chronic pancreatitisChymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme YRole of Biomarkers in Diagnosis and Prognostic Evaluation of Acute PancreatitisAcute pancreatitis in children and adolescentsPathophysiology of acute pancreatitis: potential application from experimental models and human medicine to dogsStructural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsinDeterminants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with MesotrypsinThe P 2 ′ residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activityLong-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme ActivationPresence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitorsChymotrypsin C mutations in chronic pancreatitis.Activation of recombinant proenteropeptidase by duodenaseMolecular dynamics simulations reveal structural instability of human trypsin inhibitor upon D50E and Y54H mutations.Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell deathHigh Prevalence of Serine Protease Inhibitor Kazal Type 1 Gene Variations Detected by Whole Gene Sequencing in Patients with Fibrocalculous Pancreatic Diabetes.Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway.Luminal endocytosis and intracellular targeting by acinar cells during early biliary pancreatitis in the opossumPancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice after subchronic exposure to ethanolReview of feline pancreatitis part one: the normal feline pancreas, the pathophysiology, classification, prevalence and aetiologies of pancreatitis.Review of feline pancreatitis part two: clinical signs, diagnosis and treatment.Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis.Chronic pancreatitis and cystic fibrosis.Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancersTighter Control by Chymotrypsin C (CTRC) Explains Lack of Association between Human Anionic Trypsinogen and Hereditary Pancreatitis.Biochemical and structural insights into mesotrypsin: an unusual human trypsin.Minigene analysis of intronic variants in common SPINK1 haplotypes associated with chronic pancreatitis.Signal peptide variants that impair secretion of pancreatic secretory trypsin inhibitor (SPINK1) cause autosomal dominant hereditary pancreatitisZymogen activation confers thermodynamic stability on a key peptide bond and protects human cationic trypsin from degradation.Human trypsinogens in the pancreas and in cancer.Animal models for investigating chronic pancreatitis.Management of acute pancreatitis in dogs: a critical appraisal with focus on feeding and analgesia.Diabetes mellitus and pancreatitis--cause or effect?Biomarker development, from bench to bedside.Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation.In vitro secretion of zymogens by bovine pancreatic acini and ultra-structural analysis of exocytosisHuman cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis.Expression of matrix proteinases during human intrahepatic bile duct development. A possible role in biliary cell migration.Detection of oncogenes in chronic pancreatitis.Pancreatitis from intestinal reflux--again?
P2860
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P2860
Activation of pancreatic zymogens. Normal activation, premature intrapancreatic activation, protective mechanisms against inappropriate activation.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Activation of pancreatic zymog ...... inst inappropriate activation.
@en
Activation of pancreatic zymog ...... inst inappropriate activation.
@nl
type
label
Activation of pancreatic zymog ...... inst inappropriate activation.
@en
Activation of pancreatic zymog ...... inst inappropriate activation.
@nl
prefLabel
Activation of pancreatic zymog ...... inst inappropriate activation.
@en
Activation of pancreatic zymog ...... inst inappropriate activation.
@nl
P356
P1476
Activation of pancreatic zymog ...... inst inappropriate activation.
@en
P2093
H Rinderknecht
P2888
P304
P356
10.1007/BF01318124
P577
1986-03-01T00:00:00Z