Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones.
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Polymeric Nanoparticles of Brazilian Red Propolis Extract: Preparation, Characterization, Antioxidant and Leishmanicidal Activity.Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania majorGlyoxalase I gene deletion mutants of Leishmania donovani exhibit reduced methylglyoxal detoxificationProtein network prediction and topological analysis in Leishmania major as a tool for drug target selection.The antiparasitic compound licochalcone a is a potent echinocytogenic agent that modifies the erythrocyte membrane in the concentration range where antiplasmodial activity is observed.Promising therapeutic targets for antileishmanial drugs.The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity.Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone.Antiplasmodial chalcones inhibit sorbitol-induced hemolysis of Plasmodium falciparum-infected erythrocytes.Drug delivery strategies for therapy of visceral leishmaniasis.Mitochondria and trypanosomatids: targets and drugs.The 8-aminoquinoline analogue sitamaquine causes oxidative stress in Leishmania donovani promastigotes by targeting succinate dehydrogenase.Pharmacological Effects of Glycyrrhiza spp. and Its Bioactive Constituents: Update and Review.QSAR-driven design, synthesis and discovery of potent chalcone derivatives with antitubercular activity.The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases.Synthesis, leishmanicidal and cytotoxic activity of triclosan-chalcone, triclosan-chromone and triclosan-coumarin hybrids.4-amino bis-pyridinium derivatives as novel antileishmanial agents.Licochalcone A as a potent antitumor agent suppresses growth of human oral cancer SCC-25 cells in vitro via caspase-3 dependent pathways.Antibacterial activity of licochalcone A against spore-forming bacteria.Trypanocidal and leishmanicidal properties of substitution-containing chalcones.Miltefosine (hexadecylphosphocholine) inhibits cytochrome c oxidase in Leishmania donovani promastigotes.Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum.Fungus-elicited metabolites from plants as an enriched source for new leishmanicidal agents: antifungal phenyl-phenalenone phytoalexins from the banana plant (Musa acuminata) target mitochondria of Leishmania donovani promastigotes.Succinate secreted by Trypanosoma brucei is produced by a novel and unique glycosomal enzyme, NADH-dependent fumarate reductase.New eco-friendly animal bone meal catalysts for preparation of chalcones and aza-Michael adductsTafenoquine, an antiplasmodial 8-aminoquinoline, targets leishmania respiratory complex III and induces apoptosisA mitochondrial NADH-dependent fumarate reductase involved in the production of succinate excreted by procyclic Trypanosoma brucei.Multi-analytical platform metabolomic approach to study miltefosine mechanism of action and resistance in Leishmania.Nanoformulations of albendazole as effective anticancer and antiparasite agents.
P2860
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P2860
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
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2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones.
@en
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones.
@nl
type
label
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones.
@en
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones.
@nl
prefLabel
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones.
@en
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones.
@nl
P2093
P2860
P1476
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones
@en
P2093
P2860
P304
P356
10.1128/AAC.45.7.2023-2029.2001
P407
P577
2001-07-01T00:00:00Z