Tafenoquine, an antiplasmodial 8-aminoquinoline, targets leishmania respiratory complex III and induces apoptosis
about
Recent developments in drug discovery for leishmaniasis and human African trypanosomiasisLeishmania donovani develops resistance to drug combinationsSoulamarin isolated from Calophyllum brasiliense (Clusiaceae) induces plasma membrane permeabilization of Trypanosoma cruzi and mytochondrial dysfunctionIdentification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection.Allicin Induces Calcium and Mitochondrial Dysregulation Causing Necrotic Death in Leishmania.The Oral Antimalarial Drug Tafenoquine Shows Activity against Trypanosoma brucei.The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity.Investigation of Calcium Channel Blockers as Antiprotozoal Agents and Their Interference in the Metabolism of Leishmania (L.) infantum.The double-edged sword in pathogenic trypanosomatids: the pivotal role of mitochondria in oxidative stress and bioenergeticsInteractions between tafenoquine and artemisinin-combination therapy partner drug in asexual and sexual stage Plasmodium falciparumMitochondria and trypanosomatids: targets and drugs.Redox metabolism in mitochondria of trypanosomatidsThe 8-aminoquinoline analogue sitamaquine causes oxidative stress in Leishmania donovani promastigotes by targeting succinate dehydrogenase.Mechanisms of action of substituted β-amino alkanols on Leishmania donovani.4-amino bis-pyridinium derivatives as novel antileishmanial agents.Antileishmanial activity and evaluation of the mechanism of action of strychnobiflavone flavonoid isolated from Strychnos pseudoquina against Leishmania infantum.A recombinant chimeric protein composed of human and mice-specific CD4+ and CD8+ T-cell epitopes protects against visceral leishmaniasis.Investigation of the Anti-Leishmania (Leishmania) infantum Activity of Some Natural Sesquiterpene Lactones.Mitochondrial Proteomics of Antimony and Miltefosine Resistant Leishmania infantum.4-Aminoquinoline Derivatives as Potential Antileishmanial Agents.Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania majorInduction of mitochondrial dysfunction and oxidative stress in Leishmania donovani by orally active clerodane diterpeneActivity of imidazole compounds on Leishmania (L.) infantum chagasi: reactive oxygen species induced by econazole.Siccanin Is a Novel Selective Inhibitor of Trypanosomatid Complex II (Succinate-Ubiquinone Reductase) and a Potent Broad-Spectrum Anti-trypanosomatid Drug Candidate
P2860
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P2860
Tafenoquine, an antiplasmodial 8-aminoquinoline, targets leishmania respiratory complex III and induces apoptosis
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
@zh-cn
name
Tafenoquine, an antiplasmodial ...... plex III and induces apoptosis
@en
Tafenoquine, an antiplasmodial ...... plex III and induces apoptosis
@nl
type
label
Tafenoquine, an antiplasmodial ...... plex III and induces apoptosis
@en
Tafenoquine, an antiplasmodial ...... plex III and induces apoptosis
@nl
prefLabel
Tafenoquine, an antiplasmodial ...... plex III and induces apoptosis
@en
Tafenoquine, an antiplasmodial ...... plex III and induces apoptosis
@nl
P2860
P50
P356
P1476
Tafenoquine, an antiplasmodial ...... plex III and induces apoptosis
@en
P2093
Juan Román Luque-Ortega
Luis Carvalho
P2860
P304
P356
10.1128/AAC.00790-10
P407
P577
2010-09-13T00:00:00Z