The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase.
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The role of RPGR in cilia formation and actin stabilityNovel transglutaminase-like peptidase and C2 domains elucidate the structure, biogenesis and evolution of the ciliary compartmentThe base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalizationScrutinizing ciliopathies by unraveling ciliary interaction networksA NIMA-related kinase, CNK4, regulates ciliary stability and length.The Role of RPGR and Its Interacting Proteins in CiliopathiesA simple cell-based assay reveals that diverse neuropsychiatric risk genes converge on primary ciliaDishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarityOFD1, as a Ciliary Protein, Exhibits Neuroprotective Function in Photoreceptor Degeneration ModelsMutations in RAB28, encoding a farnesylated small GTPase, are associated with autosomal-recessive cone-rod dystrophyAn siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes"Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinasesNew interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicingInteractome analysis reveals that FAM161A, deficient in recessive retinitis pigmentosa, is a component of the Golgi-centrosomal network.Stages of ciliogenesis and regulation of ciliary lengthMeckelin is necessary for photoreceptor intraciliary transport and outer segment morphogenesisFormation of the transition zone by Mks5/Rpgrip1L establishes a ciliary zone of exclusion (CIZE) that compartmentalises ciliary signalling proteins and controls PIP2 ciliary abundancePrimary cilia and kidney injury: current research status and future perspectivesOpen Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition.Cell cycle regulation by the NEK family of protein kinases.Cilia and coordination of signaling networks during heart development.Next-generation sequencing for research and diagnostics in kidney disease.Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci.Primary Cilia in Cystic Kidney Disease.Characterizing the morbid genome of ciliopathies.Rpgrip1 is required for rod outer segment development and ciliary protein trafficking in zebrafish.Identification of a novel RPGRIP1 mutation in an Iranian family with leber congenital amaurosis by exome sequencing.The von Hippel-Lindau tumor suppressor regulates programmed cell death 5-mediated degradation of Mdm2.Regulation of E2F1 by the von Hippel-Lindau tumour suppressor protein predicts survival in renal cell cancer patients.Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry.Early presentation of cystic kidneys in a family with a homozygousINVSmutation
P2860
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P2860
The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The ciliopathy-associated prot ...... Nek4 serine/threonine kinase.
@en
The ciliopathy-associated prot ...... Nek4 serine/threonine kinase.
@nl
type
label
The ciliopathy-associated prot ...... Nek4 serine/threonine kinase.
@en
The ciliopathy-associated prot ...... Nek4 serine/threonine kinase.
@nl
prefLabel
The ciliopathy-associated prot ...... Nek4 serine/threonine kinase.
@en
The ciliopathy-associated prot ...... Nek4 serine/threonine kinase.
@nl
P2093
P2860
P50
P356
P1476
The ciliopathy-associated prot ...... h Nek4 serine/threonine kinase
@en
P2093
Dorus A Mans
Emine Bolat
Frans P M Cremers
Jeroen van Reeuwijk
Karsten Boldt
Marius Ueffing
Ronald Roepman
Stef J F Letteboer
P2860
P304
P356
10.1093/HMG/DDR280
P577
2011-06-17T00:00:00Z