Role of H-2 gene products in the function of T helper cells from normal and chimeric mice in vivo.
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Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help)Uncertainties - discrepancies in immunology.T cells respond preferentially to antigens that are similar to self H-2.Thymocyte rosettes: multicellular complexes of lymphocytes and bone marrow-derived stromal cells in the mouse thymus.Mice whose B cells cannot produce the T15 idiotype also lack an antigen-specific helper T cell required for T15 expression.Antigen-specific T cell-mediated suppression. V. H-2-linked genetic control of distinct antigen-specific defects in the production and activity of L-glutamic acid50-L-tyrosine50 suppressor factor.Gene complementation. Neither Ir-GLphi gene need be present in the proliferative T cell to generate an immune response to Poly(Glu55Lys36Phe9)n.Sendai virus-specific, H-2-restricted cytotoxic T lymphocyte responses of nude mice grafted with allogeneic or semi-allogeneic thymus glands.In vitro analysis of allogeneic lymphocyte interaction. V. Identification and characterization of two components of allogeneic effect factor, one of which displays H-2-restricted helper activity and the other, T cell-growth factor activity.Antigen-specific T cell clones restricted to unique F1 major histocompatibility complex determinants. Inhibition of proliferation with monoclonal anti-Ia antibodyEffect of helper T cells on the primary in vitro production of delayed-type hypersensitivity to influenza virus.Frequency analysis of cytotoxic T lymphocyte precursors in chimeric mice. Evidence for intrathymic maturation of clonally distinct self-major histocompatibility complex- and allo-major histocompatiblilty complex-restricted virus-specific T cells.Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia moleculesMolecular analysis of the influences of positive selection, tolerance induction, and antigen presentation on the T cell receptor repertoire.Epitopes associated with the MHC restriction site of T cells. II. Somatic generation of Iat epitopes on T cells in radiation bone marrow chimeras.T-cell-dependent B-cell stimulation is H-2 restricted and antigen dependent only at the resting B-cell levelH-2 restriction: independent recognition of H-2 and foreign antigen by a single receptorT helper cells in murine germinal centers are antigen-specific emigrants that downregulate Thy-1.Influence of H-2 antigen expression on killer T cell specificity, differentiation, and induction.H-2 restriction as a consequence of intentional priming: T cells of fully allogeneic chimeric mice as well as of normal mice respond to foreign antigens in the context of H-2 determinants not encountered on thymic epithelial cellsCharacterization of T-helper epitopes of the glycoprotein of vesicular stomatitis virusTolerance of CD8+ T cells developing in parent-->F1 chimeras prepared with supralethal irradiation: step-wise induction of tolerance in the intrathymic and extrathymic environmentsCrawling movements of lymphocytes on and beneath fibroblasts in culture.B-cell growth factor (B-cell growth factor I or B-cell-stimulating factor, provisional 1) is a differentiation factor for resting B cells and may not induce cell growth.The purified protein derivative of turberculin, a B-cell mitogen that distinguishes in its action resting, small B cells from activated B-cell blasts.Effects of blocking helper T cell induction in vivo with anti-Ia antibodies. Possible role of I-A/E hybrid molecules as restriction elements.Antigen-specific T-helper cells stimulate H-2-compatible and H-2-incompatible B-cell blasts polyclonally.Dissection of the B10.D2 anti-H-2Kb cytolytic T lymphocyte receptor repertoire.Analysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection.H-2 restriction as a consequence of intentional priming. Frequency analysis of alloantigen-restricted, trinitrophenyl-specific cytotoxic T lymphocyte precursors within thymocytes of normal mice.Failure of parental T cells to restore T-cell deficient F1 mice.
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P2860
Role of H-2 gene products in the function of T helper cells from normal and chimeric mice in vivo.
description
1978 nî lūn-bûn
@nan
1978年の論文
@ja
1978年論文
@yue
1978年論文
@zh-hant
1978年論文
@zh-hk
1978年論文
@zh-mo
1978年論文
@zh-tw
1978年论文
@wuu
1978年论文
@zh
1978年论文
@zh-cn
name
Role of H-2 gene products in t ...... mal and chimeric mice in vivo.
@en
Role of H-2 gene products in t ...... mal and chimeric mice in vivo.
@nl
type
label
Role of H-2 gene products in t ...... mal and chimeric mice in vivo.
@en
Role of H-2 gene products in t ...... mal and chimeric mice in vivo.
@nl
prefLabel
Role of H-2 gene products in t ...... mal and chimeric mice in vivo.
@en
Role of H-2 gene products in t ...... mal and chimeric mice in vivo.
@nl
P2860
P1476
Role of H-2 gene products in t ...... mal and chimeric mice in vivo.
@en
P2093
P2860
P304
P356
10.1111/J.1600-065X.1978.TB00260.X
P577
1978-01-01T00:00:00Z