Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1.
about
Global profiling of co- and post-translationally N-myristoylated proteomes in human cellsDNA methylation screening identifies driver epigenetic events of cancer cell survivalStress-inducible caspase substrate TRB3 promotes nuclear translocation of procaspase-3Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway.Reduced endoplasmic reticulum stress-induced apoptosis and impaired unfolded protein response in TRPC3-deficient M1 macrophages.Chemotherapeutic drugs induce ATP release via caspase-gated pannexin-1 channels and a caspase/pannexin-1-independent mechanism.Distinct pathways mediate axon degeneration during apoptosis and axon-specific pruningHantavirus-infection confers resistance to cytotoxic lymphocyte-mediated apoptosis.Long-term quiescent fibroblast cells transit into senescenceTwo modes of cell death caused by exposure to nanosecond pulsed electric field.Caspase-9 mediates Puma activation in UCN-01-induced apoptosis.Alpinetin inhibits lung cancer progression and elevates sensitization drug-resistant lung cancer cells to cis-diammined dichloridoplatium.The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes.Apoptosis-like cell death pathways in the unicellular parasite Toxoplasma gondii following treatment with apoptosis inducers and chemotherapeutic agents: a proof-of-concept studyConserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence.Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cellsNatural Products Diversity of Marine Ascidians (Tunicates; Ascidiacea) and Successful Drugs in Clinical Development.Effects of paclitaxel on permanent head and neck squamous cell carcinoma cell lines and identification of anti-apoptotic caspase 9b.Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis.Mitochondrial mechanisms of neuronal rescue by F-68, a hydrophilic Pluronic block co-polymer, following acute substrate deprivation.A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image AnalysisArtesunate induces necrotic cell death in schwannoma cells.Melatonin prevents chemical-induced haemopoietic cell death.Loss of Bcl-2 expression correlates with increasing sensitivity to apoptosis in differentiating ES cells.Structural elaboration of a natural product: identification of 3,3'-diindolylmethane aminophosphonate and urea derivatives as potent anticancer agents.PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.Cadmium-induced apoptosis of Siberian tiger fibroblasts via disrupted intracellular homeostasisEBNA3C-mediated regulation of aurora kinase B contributes to Epstein-Barr virus-induced B-cell proliferation through modulation of the activities of the retinoblastoma protein and apoptotic caspasesApaf-1- and Caspase-8-independent apoptosis.The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression.Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization.Caspase-9 CARD : core domain interactions require a properly formed active site.Daldinone derivatives from the mangrove-derived endophytic fungus Annulohypoxylon spSphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human.
P2860
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P2860
Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Triggering of a novel intrinsi ...... se-9 in the absence of Apaf-1.
@en
Triggering of a novel intrinsi ...... se-9 in the absence of Apaf-1.
@nl
type
label
Triggering of a novel intrinsi ...... se-9 in the absence of Apaf-1.
@en
Triggering of a novel intrinsi ...... se-9 in the absence of Apaf-1.
@nl
prefLabel
Triggering of a novel intrinsi ...... se-9 in the absence of Apaf-1.
@en
Triggering of a novel intrinsi ...... se-9 in the absence of Apaf-1.
@nl
P2093
P50
P356
P1433
P1476
Triggering of a novel intrinsi ...... se-9 in the absence of Apaf-1.
@en
P2093
Alexandra Dieterle
Antje Löffler
Florian Paasch
Joachim Manns
Kirsten Lauber
Klaus Schulze-Osthoff
Merle Daubrawa
Nadine Hoffmann
Stefan Driessen
Thomas Iftner
P304
P356
10.1096/FJ.10-177527
P407
P577
2011-06-09T00:00:00Z