TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer. - Wikidata - awgldk - TriplyDB

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.

http://www.wikidata.org/entity/Q39532727

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Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition TGF-β signaling via TAK1 pathway: role in kidney fibrosis Key role for ubiquitin protein modification in TGFβ signal transduction Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads Receptor tyrosine kinases in the nucleus The role of Snail in prostate cancer A Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous Systems Intertwining of Activin A and TGFβ Signaling: Dual Roles in Cancer Progression and Cancer Cell Invasion CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.miR-146a enhances the oncogenicity of oral carcinoma by concomitant targeting of the IRAK1, TRAF6 and NUMB genes.C-terminal Src kinase (Csk)-mediated phosphorylation of eukaryotic elongation factor 2 (eEF2) promotes proteolytic cleavage and nuclear translocation of eEF2 Snail acetylation by histone acetyltransferase p300 in lung cancer Strategies for exploring TGF-β signaling in Drosophila.TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1 Ectodomain shedding of TβRIII is required for TβRIII-mediated suppression of TGF-β signaling and breast cancer migration and invasion.Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells.Phosphorylation of ΔNp63α via a novel TGFβ/ALK5 signaling mechanism mediates the anti-clonogenic effects of TGFβ.Inhibition of IRAK1/4 sensitizes T cell acute lymphoblastic leukemia to chemotherapies.Signaling mechanisms of the epithelial-mesenchymal transition.Increased Expression of TGF-β Signaling Components in a Mouse Model of Fibrosis Induced by Submandibular Gland Duct Ligation.Regulation of TGF-β receptor activity Nuclear translocation of type I transforming growth factor β receptor confers a novel function in RNA processing Reprogramming during epithelial to mesenchymal transition under the control of TGFβ Two Paralogous Tetraspanins TSP-12 and TSP-14 Function with the ADAM10 Metalloprotease SUP-17 to Promote BMP Signaling in Caenorhabditis elegans TGF-β-activated kinase-1: New insights into the mechanism of TGF-β signaling and kidney disease.Expression and Clinical Significance of Tumor Necrosis Factor Receptor-Associated Factor 6 in Patients With Colon Cancer APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.An in vitro culture system for long-term expansion of epithelial and mesenchymal salivary gland cells: role of TGF-β1 in salivary gland epithelial and mesenchymal differentiation.TRAF molecules in cell signaling and in human diseases The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling.The relevance of the TGF-β Paradox to EMT-MET programs Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma.miR-4775 promotes colorectal cancer invasion and metastasis via the Smad7/TGFβ-mediated epithelial to mesenchymal transition.TGF-β: duality of function between tumor prevention and carcinogenesis.Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs.Post-translational regulation of TGF-β receptor and Smad signaling.Matters of context guide future research in TGFβ superfamily signaling.Moonlighting proteins in cancer.

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TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.

http://www.wikidata.org/entity/Q39532727

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

TRAF6 ubiquitinates TGFβ type ...... clear translocation in cancer.

@en

TRAF6 ubiquitinates TGFβ type ...... clear translocation in cancer.

@nl

type

label

TRAF6 ubiquitinates TGFβ type ...... clear translocation in cancer.

@en

TRAF6 ubiquitinates TGFβ type ...... clear translocation in cancer.

@nl

prefLabel

TRAF6 ubiquitinates TGFβ type ...... clear translocation in cancer.

@en

TRAF6 ubiquitinates TGFβ type ...... clear translocation in cancer.

@nl

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P1433

Nature Communications

P1476

TRAF6 ubiquitinates TGFβ type ...... uclear translocation in cancer

@en

P2093

Annika Hermansson

http://www.w3.org/2001/XMLSchema#string

Carl-Henrik Heldin

http://www.w3.org/2001/XMLSchema#string

Helen Dimitriou

http://www.w3.org/2001/XMLSchema#string

Maria Ekman

http://www.w3.org/2001/XMLSchema#string

Maria Teresa Bengoechea-Alonso

http://www.w3.org/2001/XMLSchema#string

Mariya Yakymovych

http://www.w3.org/2001/XMLSchema#string

Noopur Thakur

http://www.w3.org/2001/XMLSchema#string

Yabing Mu

http://www.w3.org/2001/XMLSchema#string

P2860

The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab

Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

Anti-integrin monoclonal antibodies

Epithelial-mesenchymal transitions in development and disease

The ubiquitin system

TGFbeta in Cancer

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330

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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10.1038/NCOMMS1332

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P478

2

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P50

Marene Landström

Shyam Kumar Gudey

P577

2011-01-01T00:00:00Z

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51181066

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21629263

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P921

protein ubiquitination

P932

3113296

http://www.w3.org/2001/XMLSchema#string