Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
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Senescence from G2 arrest, revisitedp21-activated kinase 7 is an oncogene in human osteosarcomaOncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic ReplicationDietary NiCl₂ causes G₂/M cell cycle arrest in the broiler's kidney.The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cellsDNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase.High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation.MicroRNA-17-5p regulated apoptosis-related protein expression and radiosensitivity in oral squamous cell carcinoma caused by betel nut chewing.Lithium causes G2 arrest of renal principal cellsChk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cellsPathways for genome integrity in G2 phase of the cell cycle.Changes in the response of MCF-7 cells to ionizing radiation after the combination of ATM and DNA-PK inhibition.Bimodal regulation of p21(waf1) protein as function of DNA damage levels.Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase.MicroRNA-17-5p post-transcriptionally regulates p21 expression in irradiated betel quid chewing-related oral squamous cell carcinoma cells.Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.Oxidative DNA damage is involved in ochratoxin A-induced G2 arrest through ataxia telangiectasia-mutated (ATM) pathways in human gastric epithelium GES-1 cells in vitro.HMGA2 inhibits apoptosis through interaction with ATR-CHK1 signaling complex in human cancer cells.In vitro radiosensitization by pentoxifylline does not depend on p53 status.Down regulation of Chk1 by p53 plays a role in synergistic induction of apoptosis by chemotherapeutics and inhibitors for Jak2 or BCR/ABL in hematopoietic cells.Tumor cell death mediated by peptides that recognize branched intermediates of DNA replication and repair.Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage.Induction of a Senescence-Like Phenotype in Cultured Human Fetal Microglia During HIV-1 Infection.New Insights into Protein Kinase B/Akt Signaling: Role of Localized Akt Activation and Compartment-Specific Target Proteins for the Cellular Radiation Response.The effect of ATM kinase inhibition on the initial response of human dental pulp and periodontal ligament mesenchymal stem cells to ionizing radiation.Camptothecin induces G2/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen species.The live cell DNA stain SiR-Hoechst induces DNA damage responses and impairs cell cycle progression.
P2860
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P2860
Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Chk1 is dispensable for G2 arr ...... p53/p21 pathway is functional.
@en
Chk1 is dispensable for G2 arr ...... p53/p21 pathway is functional.
@nl
type
label
Chk1 is dispensable for G2 arr ...... p53/p21 pathway is functional.
@en
Chk1 is dispensable for G2 arr ...... p53/p21 pathway is functional.
@nl
prefLabel
Chk1 is dispensable for G2 arr ...... p53/p21 pathway is functional.
@en
Chk1 is dispensable for G2 arr ...... p53/p21 pathway is functional.
@nl
P2093
P2860
P356
P1433
P1476
Chk1 is dispensable for G2 arr ...... /p53/p21 pathway is functional
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2011.135
P407
P577
2011-05-02T00:00:00Z