about
Heart-specific activation of LTK results in cardiac hypertrophy, cardiomyocyte degeneration and gene reprogramming in transgenic miceAneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation but is found to support aneuploidy.Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling.Insights into cancer from transgenic mouse models.Development of a flexible and specific gene delivery system for production of murine tumor models.Specific chromosomal abnormalities characterize fibrosarcomas of bovine papillomavirus type 1 transgenic mice.Obesity-linked regulation of the adipsin gene promoter in transgenic miceConditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene.Loss of p16INK4a results in increased glucocorticoid receptor activity during fibrosarcoma development.PPARgamma induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A.Allelotyping of butadiene-induced lung and mammary adenocarcinomas of B6C3F1 mice: frequent losses of heterozygosity in regions homologous to human tumor-suppressor genes.Transgenic animals in the evaluation of compound efficacy and toxicity: will they be as useful as they are novel?miR-296 regulation of a cell polarity-cell plasticity module controls tumor progression.Nonrandom cytogenetic alterations in hepatocellular carcinoma from transgenic mice overexpressing c-Myc and transforming growth factor-alpha in the liver.Genome-wide search for loss of heterozygosity in transgenic mouse tumors reveals candidate tumor suppressor genes on chromosomes 9 and 16.Selective amplification of periportal transitional cells precedes formation of hepatocellular carcinoma in SV40 large tag transgenic mice.Transgenic mice that develop pituitary tumors. A model for Cushing's diseaseDistinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-alpha. Characterization of mammary gland and skin proliferations.Endocrine pancreatic tumors in MSV-SV40 large T transgenic mice.Proliferation of endothelial component of parathyroid gland in multiple endocrine neoplasia type 1. Potential relationship with a mitogenic factor.A novel target cell for c-fos-induced oncogenesis: development of chondrogenic tumours in embryonic stem cell chimeras.Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion geneHuman COL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development.Multiple endocrine neoplasia type I: general features and new insights into etiology.Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoterInduction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigenRestriction of neuroblastoma to the prostate gland in transgenic mice.Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigensDiabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cellsThe polyomavirus early region gene in transgenic mice causes vascular and bone tumors.Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice.Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic miceA Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic CharacteristicsHibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene.DNA rearrangement causes hepatocarcinogenesis in albumin-plasminogen activator transgenic mice.MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer.Targeting of transgene expression to monocyte/macrophages by the gp91-phox promoter and consequent histiocytic malignancies.Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic miceA transition in transcriptional activation by the glucocorticoid and retinoic acid receptors at the tumor stage of dermal fibrosarcoma development.An overview of tumor biology.
P2860
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P2860
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Dissecting multistep tumorigenesis in transgenic mice.
@en
Dissecting multistep tumorigenesis in transgenic mice.
@nl
type
label
Dissecting multistep tumorigenesis in transgenic mice.
@en
Dissecting multistep tumorigenesis in transgenic mice.
@nl
prefLabel
Dissecting multistep tumorigenesis in transgenic mice.
@en
Dissecting multistep tumorigenesis in transgenic mice.
@nl
P1476
Dissecting multistep tumorigenesis in transgenic mice.
@en
P2093
P304
P356
10.1146/ANNUREV.GE.22.120188.002403
P577
1988-01-01T00:00:00Z