Gag protein epitopes recognized by ELA-A-restricted cytotoxic T lymphocytes from horses with long-term equine infectious anemia virus infection.
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The common equine class I molecule Eqca-1*00101 (ELA-A3.1) is characterized by narrow peptide binding and T cell epitope repertoires.Epitope specificity is critical for high and moderate avidity cytotoxic T lymphocytes associated with control of viral load and clinical disease in horses with equine infectious anemia virus.Gag protein epitopes recognized by CD4(+) T-helper lymphocytes from equine infectious anemia virus-infected carrier horses.Rhodococcus equi-specific cytotoxic T lymphocytes in immune horses and development in asymptomatic foalsHuman immunodeficiency virus and AIDS: insights from animal lentivirusesLymphocyte proliferation responses induced to broadly reactive Th peptides did not protect against equine infectious anemia virus challengeFailure of low-dose recombinant human IL-2 to support the survival of virus-specific CTL clones infused into severe combined immunodeficient foals: lack of correlation between in vitro activity and in vivo efficacy.Equine infectious anemia virus envelope evolution in vivo during persistent infection progressively increases resistance to in vitro serum antibody neutralization as a dominant phenotype.CTL from EIAV carrier horses with diverse MHC class I alleles recognize epitope clusters in Gag matrix and capsid proteinsEarly detection of dominant Env-specific and subdominant Gag-specific CD8+ lymphocytes in equine infectious anemia virus-infected horses using major histocompatibility complex class I/peptide tetrameric complexes.Immune reconstitution prevents continuous equine infectious anemia virus replication in an Arabian foal with severe combined immunodeficiency: lessons for control of lentiviruses.A single amino acid difference within the alpha-2 domain of two naturally occurring equine MHC class I molecules alters the recognition of Gag and Rev epitopes by equine infectious anemia virus-specific CTL.Evaluation of high functional avidity CTL to Gag epitope clusters in EIAV carrier horsesCloning and large-scale expansion of epitope-specific equine cytotoxic T lymphocytes using an anti-equine CD3 monoclonal antibody and human recombinant IL-2Development and characterization of an equine infectious anemia virus Env-pseudotyped reporter virusViral load and clinical disease enhancement associated with a lentivirus cytotoxic T lymphocyte vaccine regimen.Immune responses and viral replication in long-term inapparent carrier ponies inoculated with equine infectious anemia virus.Envelope determinants of equine infectious anemia virus vaccine protection and the effects of sequence variation on immune recognition.Identification of Rhodococcus equi lipids recognized by host cytotoxic T lymphocytes.
P2860
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P2860
Gag protein epitopes recognized by ELA-A-restricted cytotoxic T lymphocytes from horses with long-term equine infectious anemia virus infection.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Gag protein epitopes recognize ...... ctious anemia virus infection.
@en
Gag protein epitopes recognize ...... ctious anemia virus infection.
@nl
type
label
Gag protein epitopes recognize ...... ctious anemia virus infection.
@en
Gag protein epitopes recognize ...... ctious anemia virus infection.
@nl
prefLabel
Gag protein epitopes recognize ...... ctious anemia virus infection.
@en
Gag protein epitopes recognize ...... ctious anemia virus infection.
@nl
P2093
P2860
P1433
P1476
Gag protein epitopes recognize ...... ctious anemia virus infection.
@en
P2093
P2860
P304
P407
P577
1998-12-01T00:00:00Z