Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice.
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SIRT1 as a therapeutic target in inflammaging of the pulmonary diseaseSenescence in chronic obstructive pulmonary diseaseAsbestos-induced lung diseases: an updateEffects of age on the synergistic interactions between lipopolysaccharide and mechanical ventilation in mice.Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications.Anti-inflammatory effect of a selective IkappaB kinase-beta inhibitor in rat lung in response to LPS and cigarette smoke.Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad3 knockout mice.Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD.Semaphorin 3A contributes to distal pulmonary epithelial cell differentiation and lung morphogenesis.Glutaredoxin 1 regulates cigarette smoke-mediated lung inflammation through differential modulation of I{kappa}B kinases in mice: impact on histone acetylation.Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease.Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction.Hyperoxia impairs alveolar formation and induces senescence through decreased histone deacetylase activity and up-regulation of p21 in neonatal mouse lung.Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences.MicroRegulators come of age in senescence.Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs.Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cellsOxidative stress induced lung cancer and COPD: opportunities for epigenetic therapy.SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice.DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease.Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence.Deletion of p21/Cdkn1a confers protective effect against prostate tumorigenesis in transgenic adenocarcinoma of the mouse prostate modelCigarette smoke triggers code red: p21CIP1/WAF1/SDI1 switches on danger responses in the lung.Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression.P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescenceCurrent concepts on the role of inflammation in COPD and lung cancer.Cellular senescence: its role in tumor suppression and aging.Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents.A causal model of chronic obstructive pulmonary disease (COPD) risk.LPS Induces Hyper-Permeability of Intestinal Epithelial Cells.Soluble extracellular Klotho decreases sensitivity to cigarette smoke induced cell death in human lung epithelial cells.Phospholipase C-ε signaling mediates endothelial cell inflammation and barrier disruption in acute lung injury.p21(WAF1/Cip1/Sdi1) knockout mice respond to doxorubicin with reduced cardiotoxicityAging, cancer, and cancer vaccinesPulmonary epithelial neuropilin-1 deletion enhances development of cigarette smoke-induced emphysema.Genetic Ablation of p16(Ink4a) Does Not Protect Against Cellular Senescence in Mouse Models of COPD/Emphysema.Vulnerability and Genetic Susceptibility to Cigarette Smoke-Induced Emphysema in Mice.Nrf2 attenuates inflammatory response in COPD/emphysema: Crosstalk with Wnt3a/β-catenin and AMPK pathways.Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema.Altered expression of p21, activated caspase-3, and PCNA in bronchiolar epithelium of smokers with and without chronic obstructive pulmonary disease.
P2860
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P2860
Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Disruption of p21 attenuates l ...... smoke, LPS, and fMLP in mice.
@en
Disruption of p21 attenuates l ...... smoke, LPS, and fMLP in mice.
@nl
type
label
Disruption of p21 attenuates l ...... smoke, LPS, and fMLP in mice.
@en
Disruption of p21 attenuates l ...... smoke, LPS, and fMLP in mice.
@nl
prefLabel
Disruption of p21 attenuates l ...... smoke, LPS, and fMLP in mice.
@en
Disruption of p21 attenuates l ...... smoke, LPS, and fMLP in mice.
@nl
P2093
P2860
P356
P1476
Disruption of p21 attenuates l ...... e smoke, LPS, and fMLP in mice
@en
P2093
David Adenuga
Hongwei Yao
Indika Edirisinghe
Irfan Rahman
Michael A O'Reilly
Samuel Caito
Se-Ran Yang
P2860
P356
10.1165/RCMB.2007-0342OC
P577
2008-01-31T00:00:00Z