The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin.
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Evolution of energy metabolism and its compartmentation in KinetoplastidaEvasion of the Immune Response by Trypanosoma cruzi during Acute InfectionStructural and mechanistic insights into type II trypanosomatid tryparedoxin-dependent peroxidasesStructural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I)Mitochondrial redox metabolism in trypanosomatids is independent of tryparedoxin activityBis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi.pTcINDEX: a stable tetracycline-regulated expression vector for Trypanosoma cruzi.Vitamin C biosynthesis in trypanosomes: a role for the glycosome.The parasite-specific trypanothione metabolism of trypanosoma and leishmania.Trypanosoma cruzi expresses a plant-like ascorbate-dependent hemoperoxidase localized to the endoplasmic reticulum.Trypanothione synthesis in crithidia revisited.Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi.The role of glutathione peroxidases in trypanosomatids.Distinct Phenotypes Caused by Mutation of MSH2 in Trypanosome Insect and Mammalian Life Cycle Forms Are Associated with Parasite Adaptation to Oxidative Stress.Trypanosoma cruzi Needs a Signal Provided by Reactive Oxygen Species to Infect MacrophagesA mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes.Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite.Trypanosoma cruzi antioxidant enzymes as virulence factors in Chagas disease.A Comparative In Silico Study of the Antioxidant Defense Gene Repertoire of Distinct Lifestyle Trypanosomatid Species.Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence.Trypanocidal drugs: mechanisms, resistance and new targets.Polyamine metabolism in Leishmania: from arginine to trypanothione.Redox metabolism in mitochondria of trypanosomatidsCatalase expression impairs oxidative stress-mediated signalling in Trypanosoma cruzi.Mechanism of genetic exchange in American trypanosomes.The terminal step in vitamin C biosynthesis in Trypanosoma cruzi is mediated by a FMN-dependent galactonolactone oxidase.Benznidazole-resistance in Trypanosoma cruzi is a readily acquired trait that can arise independently in a single population.TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum.Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites.A comparative study of type I and type II tryparedoxin peroxidases in Leishmania major.An RNA recognition motif mediates the nucleocytoplasmic transport of a trypanosome RNA-binding protein.Catalytic mechanism of the glutathione peroxidase-type tryparedoxin peroxidase of Trypanosoma brucei.A second class of peroxidases linked to the trypanothione metabolism.A putative glutathione peroxidase of Drosophila encodes a thioredoxin peroxidase that provides resistance against oxidative stress but fails to complement a lack of catalase activity.Functional and physicochemical characterization of the thioredoxin system in Trypanosoma brucei.Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols.Substrate specificity, localization, and essential role of the glutathione peroxidase-type tryparedoxin peroxidases in Trypanosoma brucei.The pentose phosphate pathway in Trypanosoma cruzi: a potential target for the chemotherapy of Chagas disease.Thiol Peroxidases of Trypanosomatids
P2860
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P2860
The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The Trypanosoma cruzi enzyme T ...... y glutathione or tryparedoxin.
@en
The Trypanosoma cruzi enzyme T ...... y glutathione or tryparedoxin.
@nl
type
label
The Trypanosoma cruzi enzyme T ...... y glutathione or tryparedoxin.
@en
The Trypanosoma cruzi enzyme T ...... y glutathione or tryparedoxin.
@nl
prefLabel
The Trypanosoma cruzi enzyme T ...... y glutathione or tryparedoxin.
@en
The Trypanosoma cruzi enzyme T ...... y glutathione or tryparedoxin.
@nl
P2093
P356
P1476
The Trypanosoma cruzi enzyme T ...... by glutathione or tryparedoxin
@en
P2093
David J Meyer
Elizabeth V Bromley
John M Kelly
Michael A Miles
Shane R Wilkinson
P304
17062-17071
P356
10.1074/JBC.M111126200
P407
P577
2002-02-12T00:00:00Z