Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber.
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Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic ApplicationsCell entry and trafficking of human adenovirus bound to blood factor X is determined by the fiber serotype and not hexon:heparan sulfate interactionProtein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysisDevelopment of a targeted gene vector platform based on simian adenovirus serotype 24.Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular classification and taxonomy.Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation.Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.Chapter two--Adenovirus strategies for tissue-specific targeting.Gene therapy progress and prospects: adenoviral vectors.Transductional targeting of adenovirus vectors for gene therapyA transductionally retargeted adenoviral vector for virotherapy of Her2/neu-expressing prostate cancer.Metabolic biotinylation of recombinant proteins in mammalian cells and in mice.Gene therapy and virotherapy of gastric cancer: preclinical results and clinical developments.Adenoviruses for treatment of cancer.Gene therapy in urology: strategies to translate theory into practice.Oncolytic adenoviruses - selective retargeting to tumor cells.Targeting EGFR with metabolically biotinylated fiber-mosaic adenovirus.Reduced infectivity of adenovirus type 5 particles and degradation of entering viral genomes associated with incomplete processing of the preterminal protein.Current advances and future challenges in Adenoviral vector biology and targetingImproved adenovirus type 5 vector-mediated transduction of resistant cells by piggybacking on coxsackie B-adenovirus receptor-pseudotyped baculovirus.Replacement of native adenovirus receptor-binding sites with a new attachment moiety diminishes hepatic tropism and enhances bioavailability in mice.Engineered adenovirus fiber shaft fusion homotrimer of soluble TRAIL with enhanced stability and antitumor activity.Therapeutic potential of adenoviral vectors for delivery of expressed RNAi activators.Adenovirus fiber shaft contains a trimerization element that supports peptide fusion for targeted gene delivery.Tropism-modification strategies for targeted gene delivery using adenoviral vectors.155R is a novel structural protein of bovine adenovirus type 3, but it is not essential for virus replication.Interaction of adenovirus type 5 fiber with the coxsackievirus and adenovirus receptor activates inflammatory response in human respiratory cells.Antibody-mediated targeting of an adenovirus vector modified to contain a synthetic immunoglobulin g-binding domain in the capsid.Re-targeted adenovirus vectors with dual specificity; binding specificities conferred by two different Affibody molecules in the fiber.Genetically targeted adenovirus vector directed to CD40-expressing cellsAn adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery.Tumor cell targeted gene delivery by adenovirus 5 vectors carrying knobless fibers with antibody-binding domains.Gene transduction and cell entry pathway of fiber-modified adenovirus type 5 vectors carrying novel endocytic peptide ligands selected on human tracheal glandular cells.Genetic manipulations of adenovirus type 5 fiber resulting in liver tropism attenuation.The effect of fiber truncations on the stability of adenovirus type 5.The maturation of murine dendritic cells induced by human adenovirus is mediated by the fiber knob domain.Mechanism of restriction of normal and cystic fibrosis transmembrane conductance regulator-deficient human tracheal gland cells to adenovirus infection and ad-mediated gene transfer.Synthesis of adenoviral targeting molecules by intein-mediated protein ligation.The alphavbeta5 integrin of hematopoietic and nonhematopoietic cells is a transduction receptor of RGD-4C fiber-modified adenoviruses.Novel integrin-targeted binding-triggered drug delivery system for methotrexate.
P2860
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P2860
Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber.
@en
Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber.
@nl
type
label
Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber.
@en
Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber.
@nl
prefLabel
Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber.
@en
Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber.
@nl
P2093
P2860
P1433
P1476
Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber.
@en
P2093
L Lindholm
M K Magnusson
P Boulanger
P2860
P304
P356
10.1128/JVI.75.16.7280-7289.2001
P407
P577
2001-08-01T00:00:00Z