Human immunodeficiency virus type 1 replication in the absence of integrase-mediated dna recombination: definition of permissive and nonpermissive T-cell lines.
about
HIV-1 gene expression: lessons from provirus and non-integrated DNALEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cellsContribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear importThe cell cycle independence of HIV infections is not determined by known karyophilic viral elements.Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in MaturationIdentification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integraseHuman immunodeficiency virus type 1 Vpu and cellular TASK proteins suppress transcription of unintegrated HIV-1 DNA.Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integrationHRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor.Identification of cellular cofactors for human immunodeficiency virus replication via a ribozyme-based genomics approachGenetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase.The HIV-1 integrase mutant R263A/K264A is 2-fold defective for TRN-SR2 binding and viral nuclear import.Molecular mechanisms of retroviral integration site selection.Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import.Genetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infectionNotable reduction in illegitimate integration mediated by a PPT-deleted, nonintegrating lentiviral vector.The inside out of lentiviral vectorsHuman immunodeficiency virus type 1 (HIV-1) Vpr enhances expression from unintegrated HIV-1 DNA.The requirement for nucleoporin NUP153 during human immunodeficiency virus type 1 infection is determined by the viral capsid.The role of unintegrated DNA in HIV infectionLentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo.Wild-type levels of human immunodeficiency virus type 1 infectivity in the absence of cellular emerin proteinCharacterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors.Understanding HIV resistance, fitness, replication capacity and compensation: targeting viral fitness as a therapeutic strategy.Methods for gene transfer to the central nervous system.The role of lysine 186 in HIV-1 integrase multimerizationConcurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trialsRaltegravir: molecular basis of its mechanism of actionEarly transcription from nonintegrated DNA in human immunodeficiency virus infection.Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutationsDNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition.Opposite transcriptional regulation of integrated vs unintegrated HIV genomes by the NF-κB pathway.Simian virus 40-based replication of catalytically inactive human immunodeficiency virus type 1 integrase mutants in nonpermissive T cells and monocyte-derived macrophagesA large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector.A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patientsHigh frequencies of resting CD4+ T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections.Characterization of the behavior of functional viral genomes during the early steps of human immunodeficiency virus type 1 infection.Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection.Integrase-defective lentiviral vectors: progress and applications.Distribution and fate of HIV-1 unintegrated DNA species: a comprehensive update
P2860
Q21245215-05FCFC2A-C94E-410A-8291-F29C68AD43B7Q24304259-29C8703C-98BF-4461-8034-504E5A3D9A33Q24814060-0B5682E2-E3CE-490C-90AC-A418E92752A3Q24816846-061C6C10-392E-470E-9AAB-7F1ADE228768Q27321347-52929FD4-9748-4E1B-AE10-5B93B72EAB99Q28282487-2BD63394-67BE-449A-8630-41F340C0E620Q30422793-20382AD9-CA6B-4DC2-9677-9D6436A0F9C0Q30452981-3C11FEFB-4275-4379-AD4C-598D8883586CQ30459386-7F93C2E9-5011-45EA-8564-E98E4E6F5199Q31127273-9BE806A4-8C27-4647-9029-9FBFD27ED1CBQ33782016-98684AD1-C898-4978-A3A7-AC4C8714F1D9Q34139212-E705544D-26D9-42BA-88A0-AF1E139A1FA5Q34249653-EF01D826-9413-4BF2-A0A6-E3B82182607CQ34350236-37BAE7F0-D896-4541-87A4-9157FFED8DD4Q34434675-C03CC31B-D59A-4F20-9C9D-884ADF8C5900Q34621737-37271ED4-05C1-488E-9FD5-0B052E26813AQ34633466-7451216D-B720-445F-9AE4-F71D501D096AQ34782531-7D3F7F00-B01C-432C-A936-5A67008F4325Q35140243-5CD6A07D-FF23-441F-8619-2BF7475CBC6CQ35143730-5A6C44BA-2AE2-4525-963A-ED5D921CB8ABQ35214991-70D1CAF9-B895-4A25-9D65-0DBBF20CDA32Q35634356-639B55A0-C406-4B4F-96D8-774A9128D5C3Q35785323-33299AB4-F0F4-44C1-A70F-727BAD303458Q35842525-5CEA8955-3992-4AE3-8A36-B601B44F1ECDQ35902332-BF14351E-0B95-468F-B30B-FCAF99CF246CQ36291616-2F0AC635-CF76-46C1-933A-48B07DBA8BADQ36408455-7E720DD0-6680-4655-8A7C-1DC0D12B2A71Q36452171-7A211AF3-24A3-481C-9E15-E48651016E65Q36524970-A93850A2-307B-4D09-B7EA-93107C9F14E8Q36538764-52FAC4D8-48B9-48E3-8629-044A1314F287Q36707275-17368320-01BE-4754-A31E-BE5F4404692BQ36890640-DE4F4617-0C16-45DC-852F-4E6565A00609Q36944674-293AFF17-D313-40BC-8652-06C57466C604Q36984591-EF455536-1644-4C13-8E0C-DECE81609D2FQ37030314-6A332CD2-9462-4925-A29C-DFE3AB7F9657Q37194757-AD7256BE-5582-4096-A6B5-EA6604EA3DDFQ37256671-DCF2D26A-466E-4417-90AF-240E0C040BEBQ37413470-A9B3CADB-DF26-4882-BCC1-2FECED146E74Q37619239-2587B8BB-F9A4-45E3-8378-83CE584FA72AQ37649116-A8BEFF40-52F4-4B05-A85E-3126F58F068C
P2860
Human immunodeficiency virus type 1 replication in the absence of integrase-mediated dna recombination: definition of permissive and nonpermissive T-cell lines.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Human immunodeficiency virus t ...... nd nonpermissive T-cell lines.
@en
Human immunodeficiency virus t ...... nd nonpermissive T-cell lines.
@nl
type
label
Human immunodeficiency virus t ...... nd nonpermissive T-cell lines.
@en
Human immunodeficiency virus t ...... nd nonpermissive T-cell lines.
@nl
prefLabel
Human immunodeficiency virus t ...... nd nonpermissive T-cell lines.
@en
Human immunodeficiency virus t ...... nd nonpermissive T-cell lines.
@nl
P2093
P2860
P1433
P1476
Human immunodeficiency virus t ...... nd nonpermissive T-cell lines.
@en
P2093
P2860
P304
P356
10.1128/JVI.75.17.7944-7955.2001
P407
P577
2001-09-01T00:00:00Z