Genetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infection - Wikidata - awgldk - TriplyDB

Genetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infection

Genetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infection

http://www.wikidata.org/entity/Q34434675

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All three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restriction Impact of TRIM5α in vivo Human endogenous retroviruses and the nervous system TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies Cyclophilins and nucleoporins are required for infection mediated by capsids from circulating HIV-2 primary isolates.TRIM5 alpha drives SIVsmm evolution in rhesus macaques.The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection.CCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual.Interpreting missense mutations in Human TRIM5alpha by computational methods Polymorphisms in the vitamin A receptor and innate immunity genes influence the antibody response to rubella vaccination.Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study Polymorphisms in toll-like receptor 4 and toll-like receptor 9 influence viral load in a seroincident cohort of HIV-1-infected individuals A TRIM5alpha exon 2 polymorphism is associated with protection from HIV-1 infection in the Pumwani sex worker cohort.The role of natural killer (NK) cells and NK cell receptor polymorphisms in the assessment of HIV-1 neutralization Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection How TRIM5alpha defends against retroviral invasions A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release Role of common human TRIM5alpha variants in HIV-1 disease progression Upregulation of innate antiviral restricting factor expression in the cord blood and decidual tissue of HIV-infected mothers.TRIM5α restriction affects clinical outcome and disease progression in simian immunodeficiency virus-infected rhesus macaques Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks.Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha.The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys.APOBEC3G levels predict rates of progression to AIDS Role of Human TRIM5α in Intrinsic Immunity.Host genes important to HIV replication and evolution.Host factors influencing susceptibility to HIV infection and AIDS progression.Genetic polymorphisms of Trim5a are associated with disease progression in acutely and chronically HIV-infected patients.Antiretroviral activity of ancestral TRIM5alpha.The control of viral infection by tripartite motif proteins and cyclophilin A.A naturally occurring single amino acid substitution in human TRIM5α linker region affects its anti-HIV type 1 activity and susceptibility to HIV type 1 infection.Vaccinomics, adversomics, and the immune response network theory: individualized vaccinology in the 21st century.Pressure from TRIM5α contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles.Host genes associated with HIV/AIDS: advances in gene discovery Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection Natural Killer Cell Receptor NKG2A/HLA-E Interaction Dependent Differential Thymopoiesis of Hematopoietic Progenitor Cells Influences the Outcome of HIV Infection.Impaired viral entry cannot explain reduced CD4+ T cell susceptibility to HIV type 1 in certain highly exposed individuals.

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Genetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infection

http://www.wikidata.org/entity/Q34434675

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2006 nî lūn-bûn

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Journal of Virology

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Genetic association of the ant ...... iciency virus type 1 infection

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Daniel E Geraghty

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Devon Livingston-Rosanoff

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Emily C Speelmon

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John Bui

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Lue Ping Zhao

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Quyen Vu

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Shuying Sue Li

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P2860

The tripartite motif family identifies cell compartments.

Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues

Trim5alpha protein restricts both HIV-1 and murine leukemia virus

The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities

Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha

Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

Base-calling of automated sequencer traces using phred. II. Error probabilities

Base-calling of automated sequencer traces using phred. I. Accuracy assessment

Consed: a graphical tool for sequence finishing

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