about
Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma.PD-1 and PD-L1 Expression in NSCLC Indicate a Favorable Prognosis in Defined SubgroupsElevated expression of Wnt antagonists is a common event in hepatoblastomasDevelopmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells.Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features.TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entitiesDifferential diagnosis of solitary fibrous tumors: A study of 454 soft tissue tumors indicating the diagnostic value of nuclear STAT6 relocation and ALDH1 expression combined with in situ proximity ligation assay.Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells.Perioperative chemotherapy in gastroesophageal cancer. A retrospective monocenter evaluation of 42 cases.ROS1 rearrangements in lung adenocarcinoma: prognostic impact, therapeutic options and genetic variability.Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomasTargeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity.HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat.Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells.Combinatorial effects of doxorubicin and retargeted tissue factor by intratumoral entrapment of doxorubicin and proapoptotic increase of tumor vascular infarction.MiR-34a deficiency accelerates medulloblastoma formation in vivo.Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomasTargeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G.SRC signaling is crucial in the growth of synovial sarcoma cells.MicroRNA profiling of primary high-grade soft tissue sarcomas.Combination of hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas.Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas.Differential forms of p53 in medulloblastoma primary tumors, cell lines and xenografts.Prognostic relevance of clinical and biological risk factors in childhood medulloblastoma: results of patients treated in the prospective multicenter trial HIT'91.The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo.Clinicopathological Characteristics of RET Rearranged Lung Cancer in European Patients.Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF-dependent transcription in medulloblastomas.SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas.NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas.Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN.Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas.No evidence for mutations or altered expression of the Suppressor of Fused gene (SUFU) in primitive neuroectodermal tumours.Allelic loss but absence of mutations in the polyspecific transporter gene BWR1A on 11p15.5 in hepatoblastoma.IGF-II and IL-2 act synergistically to alter HDAC1 expression following treatments with trichostatin a.Prognostic relevance of global histone H3 lysine 4 (H3K4) methylation in renal cell carcinoma.Analysis of HIC-1 methylation and transcription in human ependymomas.Differential Pi3K-pathway activation in cortical tubers and focal cortical dysplasias with balloon cells.Subtype-specific expression and genetic alterations of the chemokinereceptor gene CXCR4 in medulloblastomas.FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma.IGF-II enhances trichostatin A-induced TGFbeta1 and p21(Waf1,Cip1, sdi1) expression in Hep3B cells.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Wolfgang Hartmann
@ast
Wolfgang Hartmann
@en
Wolfgang Hartmann
@es
Wolfgang Hartmann
@nl
Wolfgang Hartmann
@sl
type
label
Wolfgang Hartmann
@ast
Wolfgang Hartmann
@en
Wolfgang Hartmann
@es
Wolfgang Hartmann
@nl
Wolfgang Hartmann
@sl
prefLabel
Wolfgang Hartmann
@ast
Wolfgang Hartmann
@en
Wolfgang Hartmann
@es
Wolfgang Hartmann
@nl
Wolfgang Hartmann
@sl
P1053
G-1893-2017
P106
P21
P31
P3829
P496
0000-0002-7609-5021