Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN.
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Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsPI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastomaNot so Fast: Co-Requirements for Sonic Hedgehog Induced Brain TumorigenesisCytomegalovirus in human brain tumors: Role in pathogenesis and potential treatment optionsBrain tumor stem cells: Molecular characteristics and their impact on therapyThe therapeutic potential of targeting the PI3K pathway in pediatric brain tumorsHeterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.AKT and its related molecular feature in aged mice skin.Integrated analysis of miRNA and mRNA expression in childhood medulloblastoma compared with neural stem cellsNovel agents targeting the IGF-1R/PI3K pathway impair cell proliferation and survival in subsets of medulloblastoma and neuroblastoma.A prognostic analysis of pediatrics central nervous system small cell tumors: evaluation of EGFR family gene amplification and overexpression.Artemether combined with shRNA interference of vascular cell adhesion molecule-1 significantly inhibited the malignant biological behavior of human glioma cells.DJ-1 is activated in medulloblastoma and is associated with cell proliferation and differentiationTargeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin.A phase I trial of MK-2206 in children with refractory malignancies: a Children's Oncology Group study.An animal model of MYC-driven medulloblastomaThe micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma.PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.The p53 codon 72 polymorphism is associated with risk and early onset of breast cancer among Saudi women.Phosphoinositide-3-kinase, catalytic, alpha polypeptide RNA interference inhibits growth of colon cancer cell SW948.Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency.Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes.Coexpression of neuronatin splice forms promotes medulloblastoma growth.The rationale for targeted therapies in medulloblastoma.Pediatric brain tumors: current treatment strategies and future therapeutic approachesPolymorphisms of insulin receptor substrate 2 are putative biomarkers for pediatric medulloblastoma: considering the genetic susceptibility and pathological diagnoses.Pediatric Ependymoma: A Proteomics Perspective.SRC inhibition represents a potential therapeutic strategy in liposarcoma.The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapyInhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma.miR-106b is overexpressed in medulloblastomas and interacts directly with PTEN.Apoptosis induced by ZnPcH1-based photodynamic therapy in Jurkat cells and HEL cells.Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways.miR-148a-3p overexpression contributes to glomerular cell proliferation by targeting PTEN in lupus nephritis.Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model.BCCIP suppresses tumor initiation but is required for tumor progressionIDO1 involvement in mTOR pathway: a molecular mechanism of resistance to mTOR targeting in medulloblastoma.Inhibition of PI3K Signalling Selectively Affects Medulloblastoma Cancer Stem Cells.The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities.PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.
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P2860
Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Phosphatidylinositol 3'-kinase ...... th reduced expression of PTEN.
@en
type
label
Phosphatidylinositol 3'-kinase ...... th reduced expression of PTEN.
@en
prefLabel
Phosphatidylinositol 3'-kinase ...... th reduced expression of PTEN.
@en
P2093
P1476
Phosphatidylinositol 3'-kinase ...... th reduced expression of PTEN.
@en
P2093
Arend Koch
Boris Digon-Söntgerath
Cynthia G Goodyer
Dorota Denkhaus
Elmar Endl
Indra Dani
Niels Sörensen
Otmar D Wiestler
Torsten Pietsch
P304
P356
10.1158/1078-0432.CCR-05-2187
P407
P577
2006-05-01T00:00:00Z