about
pH sensing and regulation in cancerIon channels and transporters in tumour cell migration and invasionEndogenous electric fields as guiding cue for cell migrationSpontaneous and electric field-controlled front-rear polarization of human keratinocytesCancer: fundamentals behind pH targeting and the double-edged approachAcidic priming enhances metastatic potential of cancer cells.PDGFRα signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90RSK and AKT signaling pathwaysTheoretical predictions of lactate and hydrogen ion distributions in tumours.Stimulation of Na(+)/H(+) exchanger isoform 1 promotes microglial migrationProlactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer CellsInversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.RhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport, cytoskeletal organization and migration.Drug resistance and cellular adaptation to tumor acidic pH microenvironmentThe human Na(+)/H(+) exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function.Actin-interacting Protein 1 Promotes Disassembly of Actin-depolymerizing Factor/Cofilin-bound Actin Filaments in a pH-dependent Manner.Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signalingElectrophoresis of cellular membrane components creates the directional cue guiding keratocyte galvanotaxisSoluble adenylyl cyclase is essential for proper lysosomal acidificationCD44 targets Na(+)/H(+) exchanger 1 to mediate MDA-MB-231 cells' metastasis via the regulation of ERK1/2.Inside out: targeting NHE1 as an intracellular and extracellular regulator of cancer progression.Roles of ion transport in control of cell motility.Involvement of tumor acidification in brain cancer pathophysiology.Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors.Carbonic anhydrase IX: a hypoxia-controlled "catalyst" of cell migration.Nanoparticle-based luminescent probes for intracellular sensing and imaging of pH.Osmotic shrinkage elicits FAK- and Src phosphorylation and Src-dependent NKCC1 activation in NIH3T3 cells.Functional interdependence of NHE1 and merlin in human melanoma cells.The Na+ /H+ -exchanger (NHE1) generates pH nanodomains at focal adhesions.Alternating pH landscapes shape epithelial cancer initiation and progression: Focus on pancreatic cancer.On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetryThe effect of carbonic anhydrase IX on focal contacts during cell spreading and migration.Extracellular protonation modulates cell-cell interaction mechanics and tissue invasion in human melanoma cells.Na(+) /H(+) exchanger 1 (NHE1) function is necessary for maintaining mammary tissue architecture.Regulating contractility of the actomyosin cytoskeleton by pH.Sarcolemmal localisation of Na+/H+ exchange and Na+-HCO3- co-transport influences the spatial regulation of intracellular pH in rat ventricular myocytes.Diesel exhaust particles induce aberrant alveolar epithelial directed cell movement by disruption of polarity mechanisms.A bioenergetic mechanism for amoeboid-like cell motility profiles tested in a microfluidic electrotaxis assay.Local pH Monitoring of Small Cluster of Cells using a Fiber-Optic Dual-Core Micro-Probe.Acid-mediated tumour cell invasion: a discrete modelling approach using the extended Potts model.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Intracellular pH gradients in migrating cells.
@en
Intracellular pH gradients in migrating cells.
@nl
type
label
Intracellular pH gradients in migrating cells.
@en
Intracellular pH gradients in migrating cells.
@nl
prefLabel
Intracellular pH gradients in migrating cells.
@en
Intracellular pH gradients in migrating cells.
@nl
P2093
P2860
P1476
Intracellular pH gradients in migrating cells.
@en
P2093
Albrecht Schwab
Christian Stock
Christine Martin
P2860
P304
P356
10.1152/AJPCELL.00280.2010
P577
2010-12-09T00:00:00Z