Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP.
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The role of mutation in the new cancer paradigmData quality in predictive toxicology: reproducibility of rodent carcinogenicity experiments.In silico toxicology: computational methods for the prediction of chemical toxicityComputational methods for prediction of in vitro effects of new chemical structuresBioalerts: a python library for the derivation of structural alerts from bioactivity and toxicity data setsDisruptive environmental chemicals and cellular mechanisms that confer resistance to cell deathPreclinical evaluation of novel antibacterial agents by microbiological and molecular techniquesTransformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedureHazard evaluation of chemicals that cause accumulation of alpha 2u-globulin, hyaline droplet nephropathy, and tubule neoplasia in the kidneys of male ratsPerspectives on the risk assessment for nongenotoxic carcinogens and tumor promotersAn open source multistep model to predict mutagenicity from statistical analysis and relevant structural alerts.Data selection and treatment of chemicals tested for genotoxicity and carcinogenicity.Correlation between mutagenicity of airborne particles and air pollution parameters in eleven Italian towns.Predicting the carcinogenicity of chemicals in humans from rodent bioassay data.Chemical carcinogenesis: too many rodent carcinogensAssessment of immunosuppressant drug carcinogenicity: standard and alternative animal models.The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st century.ToxAlerts: a Web server of structural alerts for toxic chemicals and compounds with potential adverse reactionsRisk assessment of packaging materials.A mechanism-mediated model for carcinogenicity: model content and prediction of the outcome of rodent carcinogenicity bioassays currently being conducted on 25 organic chemicals.Comparison of in silico models for prediction of mutagenicity.A retrospective evaluation of COMPACT predictions of the outcome of NTP rodent carcinogenicity testing.Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models.DNA lesions, inducible DNA repair, and cell division: three key factors in mutagenesis and carcinogenesis.Site-specific cell proliferation in renal tubular cells by the renal tubular carcinogen tris(2,3-dibromopropyl)phosphateCytochrome P-450 monooxygenase systems in aquatic species: carcinogen metabolism and biomarkers for carcinogen and pollutant exposureGenetic toxicology: current status of methods of carcinogen identificationCorrelations between chemically related site-specific carcinogenic effects in long-term studies in rats and mice.Relationship between molecular connectivity and carcinogenic activity: a confirmation with a new software program based on graph theoryTransformation of BALB/c-3T3 cells: III. Development of a co-culture clonal survival assay for quantification of chemical cytotoxicity in high-density cell culturesTransformation of BALB/c-3T3 cells: V. Transformation responses of 168 chemicals compared with mutagenicity in Salmonella and carcinogenicity in rodent bioassaysTransformation of BALB/c-3T3 cells: II. Investigation of experimental parameters that influence detection of benzo[a]pyrene-induced transformation.Interpretation of male rat renal tubule tumorsHazard identification: efficiency of short-term tests in identifying germ cell mutagens and putative nongenotoxic carcinogens.The traditional toxicologic paradigm is correct: dose influences mechanismNonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth controlMultifactor potency scheme for comparing the carcinogenic activity of chemicals.The genetic toxicity database of the National Toxicology Program: evaluation of the relationships between genetic toxicity and carcinogenicity.Structure-activity relations: maximizing the usefulness of mutagenicity and carcinogenicity databasesCharacteristics of the U.S. EPA's Office of Pesticide Programs' toxicity information databases.
P2860
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P2860
Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Chemical structure, Salmonella ...... n rodents by the U.S. NCI/NTP.
@en
Chemical structure, Salmonella ...... n rodents by the U.S. NCI/NTP.
@nl
type
label
Chemical structure, Salmonella ...... n rodents by the U.S. NCI/NTP.
@en
Chemical structure, Salmonella ...... n rodents by the U.S. NCI/NTP.
@nl
prefLabel
Chemical structure, Salmonella ...... n rodents by the U.S. NCI/NTP.
@en
Chemical structure, Salmonella ...... n rodents by the U.S. NCI/NTP.
@nl
P1433
P1476
Chemical structure, Salmonella ...... n rodents by the U.S. NCI/NTP.
@en
P2093
P304
P356
10.1016/0165-1218(88)90114-0
P407
P577
1988-01-01T00:00:00Z