The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone.
about
AlphaS1-casein, which is essential for efficient ER-to-Golgi casein transport, is also present in a tightly membrane-associated formTransient covalent interactions of newly synthesized thyroglobulin with oxidoreductases of the endoplasmic reticulumCis and trans actions of the cholinesterase-like domain within the thyroglobulin dimer.New insights into thyroglobulin pathophysiology revealed by the study of a family with congenital goiter.Neuroligin trafficking deficiencies arising from mutations in the alpha/beta-hydrolase fold protein familyRepeat motif-containing regions within thyroglobulin.Maturation of thyroglobulin protein region I.Phylogenetic analysis of the human thyroglobulin regions.Thyroglobulin From Molecular and Cellular Biology to Clinical Endocrinology.Dominant protein interactions that influence the pathogenesis of conformational diseases.A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth.Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ.Processing of cholinesterase-like α/β-hydrolase fold proteins: alterations associated with congenital disorders.Congenital hypothyroidism mutations affect common folding and trafficking in the α/β-hydrolase fold proteinsThe cholinesterase-like domain, essential in thyroglobulin trafficking for thyroid hormone synthesis, is required for protein dimerization.Relationship between the dimerization of thyroglobulin and its ability to form triiodothyronine.Importance of molecular genetic analysis in the diagnosis and classification of congenital hypothyroidism.
P2860
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P2860
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone.
@en
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone.
@nl
type
label
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone.
@en
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone.
@nl
prefLabel
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone.
@en
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone.
@nl
P2860
P356
P1476
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone
@en
P2093
Peter Arvan
P2860
P304
P356
10.1172/JCI35164
P407
P577
2008-08-01T00:00:00Z