Production of functional glucagon-secreting α-cells from human embryonic stem cells. - Wikidata - awgldk - TriplyDB

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

http://www.wikidata.org/entity/Q39640477

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Recent Advances in Disease Modeling and Drug Discovery for Diabetes Mellitus Using Induced Pluripotent Stem Cells Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement Knowledge Gaps in Rodent Pancreas Biology: Taking Human Pluripotent Stem Cell-Derived Pancreatic Beta Cells into Our Own Hands Generation of β cells from human pluripotent stem cells: are we there yet?Advances and challenges in the differentiation of pluripotent stem cells into pancreatic β cells Recent developments in β-cell differentiation of pluripotent stem cells induced by small and large molecules New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism Concise review: pancreas regeneration: recent advances and perspectives A scalable system for production of functional pancreatic progenitors from human embryonic stem cells Small-molecule inhibitors of the cystic fibrosis transmembrane conductance regulator increase pancreatic endocrine cell development in rat and mouse Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation.Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directions.Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells.Alteration of the glucagon axis in GPR120 (FFAR4) knockout mice: a role for GPR120 in glucagon secretion.Systematically labeling developmental stage-specific genes for the study of pancreatic β-cell differentiation from human embryonic stem cells.Human pluripotent stem cells: an emerging model in developmental biology.Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.In vitro differentiation and expansion of human pluripotent stem cell-derived pancreatic progenitors.Maturation of stem cell-derived beta-cells guided by the expression of urocortin 3.Initial cell seeding density influences pancreatic endocrine development during in vitro differentiation of human embryonic stem cells.Treating diet-induced diabetes and obesity with human embryonic stem cell-derived pancreatic progenitor cells and antidiabetic drugs.Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes.The Role of ARX in Human Pancreatic Endocrine Specification.Minireview: Directed Differentiation and Encapsulation of Islet β-Cells-Recent Advances and Future Considerations.Self-renewing endodermal progenitor lines generated from human pluripotent stem cells Suppression of epithelial-to-mesenchymal transitioning enhances ex vivo reprogramming of human exocrine pancreatic tissue toward functional insulin-producing β-like cells.Reprogramming adult human dermal fibroblasts to islet-like cells by epigenetic modification coupled to transcription factor modulation.Cell therapy for type 1 diabetes.iPS cells in type 1 diabetes research and treatment.Stem cell-based approaches for the treatment of diabetes.Potential pathways to restore β-cell mass: pluripotent stem cells, reprogramming, and endogenous regeneration.Restoring insulin production for type 1 diabetes.Potential for pharmacological manipulation of human embryonic stem cells.Generation of beta cells from human pluripotent stem cells: Potential for regenerative medicine.α-cell role in β-cell generation and regeneration.Endodermal stem cell populations derived from pluripotent stem cells.Making β cells from adult cells within the pancreas.Concise review: pluripotent stem cell-based regenerative applications for failing β-cell function

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P2860

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

http://www.wikidata.org/entity/Q39640477

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

@en

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

@nl

type

label

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

@en

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

@nl

prefLabel

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

@en

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

@nl

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P1476

Production of functional glucagon-secreting α-cells from human embryonic stem cells.

@en

P2093

Alireza Rezania

http://www.w3.org/2001/XMLSchema#string

Francis Karanu

http://www.w3.org/2001/XMLSchema#string

Garth L Warnock

http://www.w3.org/2001/XMLSchema#string

Michael J Riedel

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Rhonda D Wideman

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Ziliang Ao

http://www.w3.org/2001/XMLSchema#string

P2860

PAX4 enhances beta-cell differentiation of human embryonic stem cells

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

Control of endodermal endocrine development by Hes-1

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.

Depletion of definitive gut endoderm in Sox17-null mutant mice

Regulation of pancreas development by hedgehog signaling

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239-247

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10.2337/DB10-0573

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1

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60

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Timothy J Kieffer

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2010-10-22T00:00:00Z

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47534752

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20971966

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3012176

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