Reduced infectivity of a Leishmania donovani biopterin transporter genetic mutant and its use as an attenuated strain for vaccination.
about
Development of novel prime-boost strategies based on a tri-gene fusion recombinant L. tarentolae vaccine against experimental murine visceral leishmaniasisLive vaccination tactics: possible approaches for controlling visceral leishmaniasisGenetically modified organisms and visceral leishmaniasisBiomarkers of safety and immune protection for genetically modified live attenuated leishmania vaccines against visceral leishmaniasis - discovery and implications.Characterization of a Leishmania stage-specific mitochondrial membrane protein that enhances the activity of cytochrome c oxidase and its role in virulenceLive nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis.Visceral Leishmaniasis: Advancements in Vaccine Development via Classical and Molecular ApproachesKnockout of the dhfr-ts gene in Trypanosoma cruzi generates attenuated parasites able to confer protection against a virulent challenge.Development of Vaccines against Visceral LeishmaniasisLeishmania infantum HSP70-II null mutant as candidate vaccine against leishmaniasis: a preliminary evaluation.Genetically Engineered Ascorbic acid-deficient Live Mutants of Leishmania donovani induce long lasting Protective Immunity against Visceral Leishmaniasis.Killed but metabolically active Leishmania infantum as a novel whole-cell vaccine for visceral leishmaniasis.Recent advances in vaccines for leishmaniasis.Intradermal Immunization of Leishmania donovani Centrin Knock-Out Parasites in Combination with Salivary Protein LJM19 from Sand Fly Vector Induces a Durable Protective Immune Response in Hamsters.Adjuvants for Leishmania vaccines: from models to clinical application.Episomally driven antisense mRNA abrogates the hyperinducible expression and function of a unique cell surface class I nuclease in the primitive trypanosomatid parasite, Crithidia luciliae.Recombinant Leishmania major secreting biologically active granulocyte-macrophage colony-stimulating factor survives poorly in macrophages in vitro and delays disease development in mice.Live attenuated Leishmania donovani p27 gene knockout parasites are nonpathogenic and elicit long-term protective immunity in BALB/c mice.The RNA-binding protein TbDRBD3 regulates the stability of a specific subset of mRNAs in trypanosomesTransgenic Leishmania and the immune response to infectionVaccine Development Against Leishmania donovani.Immunity to visceral leishmaniasis using genetically defined live-attenuated parasites.A Non-pathogenic Recombinant Leishmania Expressing Lipophosphoglycan 3 Against Experimental Infection with Leishmania infantum.Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization.Photodynamic vaccination of hamsters with inducible suicidal mutants of Leishmania amazonensis elicits immunity against visceral leishmaniasis.A new type of high affinity folic acid transporter in the protozoan parasite Leishmania and deletion of its gene in methotrexate-resistant cells.Inactivation of the Leishmania tarentolae pterin transporter (BT1) and reductase (PTR1) genes leads to viable parasites with changes in folate metabolism and hypersensitivity to the antifolate methotrexate.Distinct 3'-untranslated region elements regulate stage-specific mRNA accumulation and translation in Leishmania.Genome Plasticity in Cultured : Comparison of Early and Late PassagesGrowth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice
P2860
Q28486287-3EB943D9-1E9F-4C8F-886B-C74C374E3D3EQ28542081-AF8A96D1-CCC0-46B5-97D7-3A47C8270878Q33647026-C9EDD46B-5F7A-4098-84CB-5421F14D7E9EQ33659753-9E2109D1-220F-49C5-8210-460E691CC1B4Q34017302-27DE92E1-3F9C-404F-B85E-D6EDEA4B2176Q34033343-DCF69B00-2FAA-48F3-A000-AB63914AF24FQ34076804-C89E5D6C-E480-4B33-AFC5-3F25F000E523Q34105267-8E785CBF-8ABA-46AE-BF43-CBFE44EBB6B0Q35207606-C1485E8D-9152-40F8-9249-068575742D59Q35427832-FAF56FC2-119C-4629-86FD-19E3E8506F46Q35673111-01E57B8E-886A-41E3-9B53-B4AC770F683CQ35867177-26E07581-D54D-46EA-9BF2-2E89169854D1Q35873792-1DA7ECF6-A8B5-42EC-AE2A-DF1C1857A6C6Q35890723-534411AC-2FAE-4914-8521-35BCDB354DA3Q36021357-E24C6AAF-7A04-4A9B-A388-D99585FD211CQ36178696-3EA5799A-C105-44BC-B4F6-9349EBBEE2FCQ36374716-56A20F27-4E4B-48FE-BB79-27AB9EB7DCFCQ36625975-0116CCC8-A5AE-4C97-ACD8-6A7354CA914DQ36824014-EFEDB279-97A2-4AAE-ADAC-D262ECEFD500Q37081691-92F68C15-1FA8-4EE3-B5C4-17C3501DB267Q38012112-E2A66C8A-A761-4A9D-AB5D-D7124B26261EQ38342966-667ADCBA-FEFA-4A31-BFB9-FAA3A504E043Q40244179-AD365AC1-F3BC-45ED-8D1F-783A0CAD3685Q40957138-57D01B82-CD30-4418-B6A6-2460D773056FQ41383476-AA8CFB1A-4781-45CC-B17A-F8A17CA7FD87Q44002731-D3794460-D1EB-4E91-9B82-466ADAFA98C3Q44774846-9B138419-E082-4191-BBB6-CF04B0D430C1Q46663718-C76B34B7-1216-47DF-B3B6-F230F985091CQ57177294-77AFD964-86A0-48E2-81AF-08EEAD31C3FAQ58803575-065D4CBF-8D7B-4140-A7FC-CBBEEC02A054
P2860
Reduced infectivity of a Leishmania donovani biopterin transporter genetic mutant and its use as an attenuated strain for vaccination.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Reduced infectivity of a Leish ...... nuated strain for vaccination.
@en
Reduced infectivity of a Leish ...... nuated strain for vaccination.
@nl
type
label
Reduced infectivity of a Leish ...... nuated strain for vaccination.
@en
Reduced infectivity of a Leish ...... nuated strain for vaccination.
@nl
prefLabel
Reduced infectivity of a Leish ...... nuated strain for vaccination.
@en
Reduced infectivity of a Leish ...... nuated strain for vaccination.
@nl
P2093
P2860
P1476
Reduced infectivity of a Leish ...... nuated strain for vaccination.
@en
P2093
Ajay K Singh
Barbara Papadopoulou
Carole Dumas
Christoph Kündig
Gaétan Roy
Isabelle Fillion
Marc Ouellette
Marie Breton
Martin Olivier
P2860
P356
10.1128/IAI.70.1.62-68.2002
P407
P577
2002-01-01T00:00:00Z