p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins.
about
The transcription factor p53: not a repressor, solely an activatorP53/microRNA-34-induced metabolic regulation: new opportunities in anticancer therapyThe p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genesSystematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivityGenome-wide and species-wide in silico screening for intragenic MicroRNAs in human, mouse and chickenMYCT1-TV, a novel MYCT1 transcript, is regulated by c-Myc and may participate in laryngeal carcinogenesis.Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs.The p53 Transcriptional Network Influences Microglia Behavior and NeuroinflammationmiRNA expression profiling of the murine TH-MYCN neuroblastoma model reveals similarities with human tumors and identifies novel candidate miRNAsGenetic networks lead and follow tumor development: microRNA regulation of cell cycle and apoptosis in the p53 pathways.Global effect of inauhzin on human p53-responsive transcriptomep53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes.The tumor suppressor p53 induces expression of the pregnancy-supporting human chorionic gonadotropin (hCG) CGB7 gene.Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin β1/FAK axis.A Temperature Sensitive Variant of p53 Drives p53-Dependent MicroRNA Expression without Evidence of Widespread Post-Transcriptional Gene SilencingGrowth differentiation factor-15 encodes a novel microRNA 3189 that functions as a potent regulator of cell death.MiR-1246: a new link of the p53 family with cancer and Down syndrome.Concomitant activation of miR-107/PDCD10 and hypoxamir-210/Casp8ap2 and their role in cytoprotection during ischemic preconditioning of stem cells.MicroRNAs, wild-type and mutant p53: more questions than answers.CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor α in Human Liver.Species-specific mutual regulation of p53 and miR-138 between human, rat and mouseIntegration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks.Macro-management of microRNAs in cell cycle progression of tumor cells and its implications in anti-cancer therapy.One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.MicroRNAs in the p53 network: micromanagement of tumour suppression.The p53 miRNA interactome and its potential role in the cancer clinic.Role of miR-107 and its signaling pathways in diseases.New insights into p53 functions through its target microRNAs.The miRNA network: micro-regulator of cell signaling in cancer.The p53/microRNA connection in gastrointestinal cancer.MicroRNA miR-107 is overexpressed in pituitary adenomas and inhibits the expression of aryl hydrocarbon receptor-interacting protein in vitro.Noncoding RNAs Regulating p53 and c-Myc Signaling.Census and evaluation of p53 target genes.Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.Exploiting the p53 Pathway for Therapy.3,3'-Diindolylmethane inhibits breast cancer cell growth via miR-21-mediated Cdc25A degradation.Differential expression of circulating microRNAs in blood and haematoma samples from patients with intracerebral haemorrhage.p53 can repress transcription of cell cycle genes through a p21(WAF1/CIP1)-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.Dynamic and Modularized MicroRNA Regulation and Its Implication in Human Cancers.Interchanging heads: p53 re-composes the DREAM/MMB complex to repress transcription.
P2860
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P2860
p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
p53 activates the PANK1/miRNA- ...... and p130 cell cycle proteins.
@en
p53 activates the PANK1/miRNA- ...... and p130 cell cycle proteins.
@nl
type
label
p53 activates the PANK1/miRNA- ...... and p130 cell cycle proteins.
@en
p53 activates the PANK1/miRNA- ...... and p130 cell cycle proteins.
@nl
prefLabel
p53 activates the PANK1/miRNA- ...... and p130 cell cycle proteins.
@en
p53 activates the PANK1/miRNA- ...... and p130 cell cycle proteins.
@nl
P2860
P356
P1476
p53 activates the PANK1/miRNA- ...... and p130 cell cycle proteins.
@en
P2093
Levin Böhlig
Maik Friedrich
P2860
P304
P356
10.1093/NAR/GKQ796
P407
P577
2010-09-10T00:00:00Z