Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing. - Wikidata - awgldk - TriplyDB

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.

http://www.wikidata.org/entity/Q39669947

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Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability DNA Damage Response and Autophagy: A Meaningful Partnership SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks.Robust, universal biomarker assay to detect senescent cells in biological specimens.Overexpression of SKP2 Inhibits the Radiation-Induced Bystander Effects of Esophageal Carcinoma.Detection of cellular senescence within human invasive breast carcinomas distinguishes different breast tumor subtypes.Sudan Black B, The Specific Histochemical Stain for Lipofuscin: A Novel Method to Detect Senescent Cells.Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex The Janus face of p21.p21WAF1/Cip1 - PCNA: Fatal attraction Inefficient differentiation response to cell cycle stress leads to genomic instability and malignant progression of squamous carcinoma cells.The cohesin complex prevents Myc-induced replication stress.Principal Aspects Regarding the Maintenance of Mammalian Mitochondrial Genome Integrity.Monitoring Autophagy Immunohistochemically and Ultrastructurally during Human Head and Neck Carcinogenesis. Relationship with the DNA Damage Response Pathway.p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress.Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells.Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics.Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.Down-regulation of MRPS23 inhibits rat breast cancer proliferation and metastasis.Systems proteomic analysis reveals that clusterin and tissue inhibitor of metalloproteinases 3 increase in leptomeningeal arteries affected by cerebral amyloid angiopathy.Transcriptomic analyses reveal the underlying pro-malignant functions of PTHR1 for osteosarcoma via activation of Wnt and angiogenesis pathways.Oncogene-Induced Replication Stress Drives Genome Instability and Tumorigenesis.Proteome Stability as a Key Factor of Genome Integrity.Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity.Ablation of epidermal RXRα in cooperation with activated CDK4 and oncogenic NRAS generates spontaneous and acute neonatal UVB induced malignant metastatic melanomas.A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.The inhibition of UBC13 expression and blockage of the DNMT1-CHFR-Aurora A pathway contribute to paclitaxel resistance in ovarian cancer.Cooperative p16 and p21 action protects female astrocytes from transformation.Genomic Destabilization Triggered by Replication Stress during Senescence.Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cells.SIRF: Quantitative in situ analysis of protein interactions at DNA replication forks.Silencing of long non-coding RNA MIR22HG triggers cell survival/death signaling via oncogenes YBX1, MET, and p21 in lung cancer.Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence.Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.PKC Dependent p14ARF Phosphorylation on Threonine 8 Drives Cell Proliferation.Cellular senescence, geroscience, cancer and beyond SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability

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P2860

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.

http://www.wikidata.org/entity/Q39669947

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Chronic p53-independent p21 ex ...... ulating replication licensing.

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Chronic p53-independent p21 ex ...... ulating replication licensing.

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type

label

Chronic p53-independent p21 ex ...... ulating replication licensing.

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Chronic p53-independent p21 ex ...... ulating replication licensing.

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prefLabel

Chronic p53-independent p21 ex ...... ulating replication licensing.

@en

Chronic p53-independent p21 ex ...... ulating replication licensing.

@nl

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Nature Cell Biology

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Chronic p53-independent p21 ex ...... ulating replication licensing.

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P2093

Akshay K Ahuja

http://www.w3.org/2001/XMLSchema#string

Alexander Polyzos

http://www.w3.org/2001/XMLSchema#string

Ana Igea

http://www.w3.org/2001/XMLSchema#string

Angel Nebreda

http://www.w3.org/2001/XMLSchema#string

Antonis Kokkalis

http://www.w3.org/2001/XMLSchema#string

Begoña Canovas

http://www.w3.org/2001/XMLSchema#string

Dimitris Kletsas

http://www.w3.org/2001/XMLSchema#string

Dimitris Thanos

http://www.w3.org/2001/XMLSchema#string

Emanuel Kanavakis

http://www.w3.org/2001/XMLSchema#string

Emma J Haagensen

http://www.w3.org/2001/XMLSchema#string

P2860

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

Nuclear dynamics of PCNA in DNA replication and repair.

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Replication licensing and cancer--a fatal entanglement?

Preventing re-replication of chromosomal DNA.

Genomic instability in cancer.

Fast gapped-read alignment with Bowtie 2

The Sequence Alignment/Map format and SAMtools

Cyclin-dependent kinases and S phase control in mammalian cells

Genomic instability--an evolving hallmark of cancer

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777-789

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scholarly article

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10.1038/NCB3378

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7

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18

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Konstantinos Vougas

Apolinar Maya-Mendoza

Panagiotis Galanos

Vassilis Gorgoulis

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2016-06-20T00:00:00Z

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27323328

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6535144

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