Identifying the functional contribution of the defatty-acylase activity of SIRT6. - Wikidata - awgldk - TriplyDB

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

http://www.wikidata.org/entity/Q39670994

about

Pyridine Dinucleotides from Molecules to Man.SIRT6: Novel Mechanisms and Links to Aging and Disease.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.Sirtuin 6 contributes to migration and invasion of osteosarcoma cells via the ERK1/2/MMP9 pathway.SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation.Exosome Theranostics: Biology and Translational Medicine.SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a.Structure-based discovery of new selective small-molecule sirtuin 5 inhibitors.Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation.SIRT7 Is an RNA-Activated Protein Lysine Deacylase.Comparative Nucleotide-Dependent Interactome Analysis Reveals Shared and Differential Properties of KRas4a and KRas4b.Sirtuin 6, a possible therapeutic target for type 2 diabetes.LC-MS/MS-based quantitative study of the acyl group- and site-selectivity of human sirtuins to acylated nucleosomes.Directed evolution of SIRT6 for improved deacylation and glucose homeostasis maintenance.

P2860

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P2860

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

http://www.wikidata.org/entity/Q39670994

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

@en

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

@nl

type

label

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

@en

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

@nl

prefLabel

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

@en

Identifying the functional contribution of the defatty-acylase activity of SIRT6.

@nl

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Nature Chemical Biology

P1476

Identifying the functional contribution of the defatty-acylase activity of SIRT6

@en

P2093

Hong Jiang

http://www.w3.org/2001/XMLSchema#string

Marc A Antonyak

http://www.w3.org/2001/XMLSchema#string

Richard A Cerione

http://www.w3.org/2001/XMLSchema#string

Saba Khan

http://www.w3.org/2001/XMLSchema#string

Xiao Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Human SIRT6 promotes DNA end resection through CtIP deacetylation

Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties

The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

Multiplex genome engineering using CRISPR/Cas systems

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

The sirtuin SIRT6 regulates lifespan in male mice

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614-620

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scholarly article

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10.1038/NCHEMBIO.2106

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8

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12

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Jonathan H Shrimp

Nicole A Spiegelman

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2016-06-20T00:00:00Z

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27322069

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4955683

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