VP40, the matrix protein of Marburg virus, is associated with membranes of the late endosomal compartment
about
Rab9 GTPase is required for replication of human immunodeficiency virus type 1, filoviruses, and measles virus.Overlapping motifs (PTAP and PPEY) within the Ebola virus VP40 protein function independently as late budding domains: involvement of host proteins TSG101 and VPS-4.Vacuolar protein sorting pathway contributes to the release of Marburg virusEbola virus infection inversely correlates with the overall expression levels of promyelocytic leukaemia (PML) protein in cultured cellsElectron tomography reveals the steps in filovirus buddingTrafficking of Sendai virus nucleocapsids is mediated by intracellular vesiclesLive-cell imaging of Marburg virus-infected cells uncovers actin-dependent transport of nucleocapsids over long distances.Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen.Establishment of fruit bat cells (Rousettus aegyptiacus) as a model system for the investigation of filoviral infectionVP40 octamers are essential for Ebola virus replication.Association of ebola virus matrix protein VP40 with microtubules.A role for the C terminus of Mopeia virus nucleoprotein in its incorporation into Z protein-induced virus-like particles.Viral and host proteins that modulate filovirus buddingBiochemical and functional characterization of the Ebola virus VP24 protein: implications for a role in virus assembly and budding.Therapeutics for filovirus infection: traditional approaches and progress towards in silico drug design.Molecular mechanism of arenavirus assembly and budding.Key genomic changes necessary for an in vivo lethal mouse marburgvirus variant selection process.Small-molecule probes targeting the viral PPxY-host Nedd4 interface block egress of a broad range of RNA viruses.Identification of amino acids in Marburg virus VP40 that are important for virus-like particle budding.Advances in virus-like particle vaccines for filoviruses.Cell-type-dependent targeting of human immunodeficiency virus type 1 assembly to the plasma membrane and the multivesicular bodyInteraction of Tsg101 with Marburg virus VP40 depends on the PPPY motif, but not the PT/SAP motif as in the case of Ebola virus, and Tsg101 plays a critical role in the budding of Marburg virus-like particles induced by VP40, NP, and GP.Forty-five years of Marburg virus research.Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression.No exit: targeting the budding process to inhibit filovirus replication.Assembly of the Marburg virus envelope.Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 to Regulate Egress.Validation of the Filovirus Plaque Assay for Use in Preclinical StudiesA Single Amino Acid Change in the Marburg Virus Matrix Protein VP40 Provides a Replicative Advantage in a Species-Specific Manner.Phosphorylation of Marburg virus matrix protein VP40 triggers assembly of nucleocapsids with the viral envelope at the plasma membrane.Investigation of the Lipid Binding Properties of the Marburg Virus Matrix Protein VP40.Tsg101 is recruited by a late domain of the nucleocapsid protein to support budding of Marburg virus-like particles.Conserved motifs within Ebola and Marburg virus VP40 proteins are important for stability, localization, and subsequent budding of virus-like particles.Lassa virus Z protein is a matrix protein and sufficient for the release of virus-like particles [corrected].Inside the Cell: Assembly of Filoviruses.Budding of Marburgvirus is associated with filopodia.Multivesicular bodies as a platform for formation of the Marburg virus envelope.Conserved proline-rich region of Ebola virus matrix protein VP40 is essential for plasma membrane targeting and virus-like particle release.VP24 of Marburg virus influences formation of infectious particles.Functional characterization of Ebola virus L-domains using VSV recombinants
P2860
Q24533383-8100709F-53BC-4C25-8905-0287DE8D40E3Q24541306-54D28A15-B2B5-462A-8A5E-99E7872983C5Q24652215-5DB2F76B-3379-4321-A16A-E4A37E60EF24Q24794365-DD1C1532-86E6-4F74-B8F7-6CEB8135EDE2Q27314945-78583048-2F7F-467B-8598-BB8DA1D1F6AAQ27325499-F755EA12-7678-41F3-9460-20CA4A018806Q30544040-1BA2D07B-49DE-4DDF-8BAD-CF6552F62B8DQ33655087-EE2D4262-24DE-46B7-973E-0EF1FD22E5EAQ33680083-BFA47FB2-4096-4399-82D5-947495AD6556Q33718451-B5632146-CD21-4C67-86DF-FE30014E83B6Q33724299-C32BE576-AFAF-4B5E-96A9-48E03C52C16FQ33826829-D10C66C9-5E6E-4CC7-9AE1-6D3734116585Q34070413-7F6DADD8-D06B-44D5-AACA-DBACE80C8DC7Q34170237-4788095F-9E12-4387-BA54-65355142C154Q34371001-CA1E8995-BCCF-411A-86FD-0036AD1E9140Q34645914-666F5077-77EC-4C20-A847-C9F49526E50FQ35076563-94AF68C7-9D6E-42C6-8D5D-316AC42A3C12Q35150964-9A237CFF-1656-4520-AE59-0BB0AE901D82Q35299826-6AA8035E-2CDB-4107-87D5-753F78D3FCC2Q35300029-90B1F3C8-8D46-4830-B437-493F95E79FACQ35543719-F7AA4635-6514-4B04-A9A8-0E60ABCBE6A5Q35857432-681106CC-02AF-4EFA-BCB5-FBC78708BFF9Q36395831-6F71898E-1795-4442-8408-27856DF53B47Q36523972-E2E0190C-5381-4A4F-97FD-70F50CF22004Q37359650-5C9A37E4-2C7B-4156-AB97-7471B8872C27Q38062931-A0C56812-F7E1-4390-B96F-3FE9FD3D7953Q38645983-B38A4742-91E5-4DBB-A2C0-38EF6CF1A4AFQ38775636-9A7A192A-7FA7-4A3C-9EEA-B41B556E73B5Q38818595-DEEDF814-4B12-4ACD-B532-3E8754F8D332Q39461698-57FA8F76-57D4-46AD-8CE9-C714DE311E45Q39603524-5CFE9C33-D800-4274-AACB-AA7D67E5249BQ39700080-265CEFDD-B4F0-4898-B263-B5DD4E7DAB4CQ39759620-ACCF15E5-A417-4C34-954E-3689E6EB45E0Q40008957-1356022A-43B4-4F18-AD4E-97C0F3BEC380Q40164595-92445CC0-E312-4965-A8B1-96E36509F183Q40202125-31F005C2-A766-48A0-A9C8-806D9D16AE61Q40277987-7A0C81CC-F1BD-4476-BFAC-03F67622D11EQ40309158-4EC1B5CB-AE95-4189-8814-0B4A9C04A35DQ40361641-A3D2BE4C-ECAD-48FE-A346-51562526D02AQ40422906-16E0111E-F209-4998-9879-79EF98138B9C
P2860
VP40, the matrix protein of Marburg virus, is associated with membranes of the late endosomal compartment
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
VP40, the matrix protein of Ma ...... the late endosomal compartment
@en
VP40, the matrix protein of Ma ...... he late endosomal compartment.
@nl
type
label
VP40, the matrix protein of Ma ...... the late endosomal compartment
@en
VP40, the matrix protein of Ma ...... he late endosomal compartment.
@nl
prefLabel
VP40, the matrix protein of Ma ...... the late endosomal compartment
@en
VP40, the matrix protein of Ma ...... he late endosomal compartment.
@nl
P2093
P2860
P1433
P1476
VP40, the matrix protein of Ma ...... the late endosomal compartment
@en
P2093
Harald Bugany
Larissa Kolesnikova
Stephan Becker
P2860
P304
P356
10.1128/JVI.76.4.1825-1838.2002
P407
P577
2002-02-01T00:00:00Z