Human T-cell leukemia virus type 2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax.
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The HTLV-1 Tax interactomeHighlights on distinctive structural and functional properties of HTLV Tax proteinsComparative biology of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2Human T-cell lymphotropic virus type 3: complete nucleotide sequence and characterization of the human tax3 proteinHuman T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell linePresence of a functional but dispensable nuclear export signal in the HTLV-2 Tax protein.Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.Rearranged NF-kappa B2 gene in an adult T-cell leukemia cell line.HTLV-1 Rex is required for viral spread and persistence in vivo but is dispensable for cellular immortalization in vitro.Induction of cell cycle arrest by human T-cell lymphotropic virus type 1 Tax in hematopoietic progenitor (CD34+) cells: modulation of p21cip1/waf1 and p27kip1 expression.Human T-cell leukemia virus type 1 expressing nonoverlapping tax and rex genes replicates and immortalizes primary human T lymphocytes but fails to replicate and persist in vivo.The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties.Molecular mechanisms of cellular transformation by HTLV-1 Tax.Long-term infection with retroviral structural gene vector provides protection against bovine leukemia virus disease in rabbits.The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoproteinInhibition of human T cell leukemia virus type 2 replication by the suppressive action of class II transactivator and nuclear factor Y.Tax and overlapping rex sequences do not confer the distinct transformation tropisms of human T-cell leukemia virus types 1 and 2Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human T-cell leukemia virus type 1 Tax proteinRecombinant human T-cell leukemia virus types 1 and 2 Tax proteins induce high levels of CC-chemokines and downregulate CCR5 in human peripheral blood mononuclear cells.Proinflammatory cytokine gene induction by human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 Tax in primary human glial cells.Detection and quantitation of HTLV-1 and HTLV-2 mRNA species by real-time RT-PCR.Human T-cell leukemia virus type 2 antisense viral protein 2 is dispensable for in vitro immortalization but functions to repress early virus replication in vivo.Deregulation of cell-signaling pathways in HTLV-1 infection.Akt Pathway Activation by Human T-cell Leukemia Virus Type 1 Tax Oncoprotein.HTLV-2 Tax immortalizes human CD4+ memory T lymphocytes by oncogenic activation and dysregulation of autophagy.Cell polarity proteins: common targets for tumorigenic human viruses.Human T-cell leukemia virus type 1 tax oncoprotein suppression of multilineage hematopoiesis of CD34+ cells in vitroHuman T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation.Functional domain structure of human T-cell leukemia virus type 2 rex.HTLV gene regulation: because size matters, transcription is not enough.Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 tax oncoproteins modulate cell cycle progression and apoptosis.Ubiquitination of human T-cell leukemia virus type 1 tax modulates its activity.Discovery and significance of new human T-lymphotropic viruses: HTLV-3 and HTLV-4.Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences.The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators.Human T-cell leukemia virus type 1 (HTLV-1) Tax1 oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52/p100 and RelB.Human T-cell leukemia virus type 1 Tax protein interacts with and mislocalizes the PDZ domain protein MAGI-1.Comparison of the Genetic Organization, Expression Strategies and Oncogenic Potential of HTLV-1 and HTLV-2.Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth.
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P2860
Human T-cell leukemia virus type 2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Human T-cell leukemia virus ty ...... s efficiently than HTLV-1 Tax.
@en
Human T-cell leukemia virus type 2
@nl
type
label
Human T-cell leukemia virus ty ...... s efficiently than HTLV-1 Tax.
@en
Human T-cell leukemia virus type 2
@nl
prefLabel
Human T-cell leukemia virus ty ...... s efficiently than HTLV-1 Tax.
@en
Human T-cell leukemia virus type 2
@nl
P2093
P2860
P1433
P1476
Human T-cell leukemia virus ty ...... s efficiently than HTLV-1 Tax.
@en
P2093
Akira Hirata
Fumitake Gejyo
Keiichi Endo
Kousuke Iwai
Mamoru Sakurai
Masahiro Fujii
Masaya Fukushi
Masaya Higuchi
Masayasu Oie
William W Hall
P2860
P304
P356
10.1128/JVI.76.6.2648-2653.2002
P407
P577
2002-03-01T00:00:00Z