Highly pathogenic simian immunodeficiency virus mne variants that emerge during the course of infection evolve enhanced infectivity and the ability to downregulate CD4 but not class I major histocompatibility complex antigens.
about
Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism.HIV-1 Transmission, Replication Fitness and Disease Progression.Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.Counteraction of HLA-C-mediated immune control of HIV-1 by Nef.Nef stimulates human immunodeficiency virus type 1 replication in primary T cells by enhancing virion-associated gp120 levels: coreceptor-dependent requirement for Nef in viral replication.Relative replication capacity of phenotypic SIV variants during primary infections differs with route of inoculation.Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptorsnef gene is required for robust productive infection by simian immunodeficiency virus of T-cell-rich paracortex in lymph nodes.Dendritic cell-mediated HIV-1 infection of T cells demonstrates a direct relationship to plasma viral RNA levelsVif substitution enables persistent infection of pig-tailed macaques by human immunodeficiency virus type 1.Phenotypic and genotypic comparisons of human T-cell leukemia virus type 1 reverse transcriptases from infected T-cell lines and patient samples.Vpx is critical for SIVmne infection of pigtail macaques.Changes in simian immunodeficiency virus reverse transcriptase alleles that appear during infection of macaques enhance infectivity and replication in CD4+ T cells.Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.Analysis of pigtail macaque major histocompatibility complex class I molecules presenting immunodominant simian immunodeficiency virus epitopes.Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection.Comprehensive analysis of nef functions selected in simian immunodeficiency virus-infected macaques.Simian immunodeficiency virus variants that differ in pathogenicity differ in fitness under rapid cell turnover conditions.
P2860
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P2860
Highly pathogenic simian immunodeficiency virus mne variants that emerge during the course of infection evolve enhanced infectivity and the ability to downregulate CD4 but not class I major histocompatibility complex antigens.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Highly pathogenic simian immun ...... ompatibility complex antigens.
@en
Highly pathogenic simian immun ...... ompatibility complex antigens.
@nl
type
label
Highly pathogenic simian immun ...... ompatibility complex antigens.
@en
Highly pathogenic simian immun ...... ompatibility complex antigens.
@nl
prefLabel
Highly pathogenic simian immun ...... ompatibility complex antigens.
@en
Highly pathogenic simian immun ...... ompatibility complex antigens.
@nl
P2093
P2860
P1433
P1476
Highly pathogenic simian immun ...... ompatibility complex antigens.
@en
P2093
Jason T Kimata
Joelle M Wilson
Julia E Biggins
Monica T Yu Kimata
Parul G Patel
P2860
P304
P356
10.1128/JVI.76.13.6425-6434.2002
P407
P577
2002-07-01T00:00:00Z