Alpha-synuclein mediates alterations in membrane conductance: a potential role for alpha-synuclein oligomers in cell vulnerability.
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Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's diseaseDopamine and paraquat enhance α-synuclein-induced alterations in membrane conductanceα-synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson's disease patientsAutonomic dysfunction and plasticity in micturition reflexes in human α-synuclein mice.α-Synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter.Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders.Dopamine Transporter Activity Is Modulated by α-Synuclein.Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein.The interplay between lipids and dopamine on α-synuclein oligomerization and membrane binding.Drug targets from genetics: α-synuclein.Misfolded α-synuclein and Toll-like receptors: therapeutic targets for Parkinson's disease.An extracellular mechanism that can explain the neurotoxic effects of α-synuclein aggregates in the brainAssociation of glycogen synthase kinase-3β with Parkinson's disease (review).Neuropathology of multiple system atrophy: new thoughts about pathogenesis.Mechanisms of alpha-synuclein action on neurotransmission: cell-autonomous and non-cell autonomous roleNumber and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells.A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.Intracellular soluble α-synuclein oligomers reduce pyramidal cell excitability.Proteasome impairment by α-synuclein.α-Synuclein Alters Toll-Like Receptor Expressionα-Synuclein oligomers pump it up!Extracellular α-synuclein alters synaptic transmission in brain neurons by perforating the neuronal plasma membrane.Alpha-Synuclein: From Early Synaptic Dysfunction to Neurodegeneration.Exogenous α-synuclein hinders synaptic communication in cultured cortical primary rat neurons.
P2860
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P2860
Alpha-synuclein mediates alterations in membrane conductance: a potential role for alpha-synuclein oligomers in cell vulnerability.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Alpha-synuclein mediates alter ...... igomers in cell vulnerability.
@en
Alpha-synuclein mediates alter ...... igomers in cell vulnerability.
@nl
type
label
Alpha-synuclein mediates alter ...... igomers in cell vulnerability.
@en
Alpha-synuclein mediates alter ...... igomers in cell vulnerability.
@nl
prefLabel
Alpha-synuclein mediates alter ...... igomers in cell vulnerability.
@en
Alpha-synuclein mediates alter ...... igomers in cell vulnerability.
@nl
P2093
P2860
P1476
Alpha-synuclein mediates alter ...... igomers in cell vulnerability.
@en
P2093
Howard J Federoff
Kathleen A Maguire-Zeiss
Li Rebekah Feng
Stefano Vicini
P2860
P356
10.1111/J.1460-9568.2010.07266.X
P407
P577
2010-06-14T00:00:00Z