Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia.
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Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/AktPhosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion.Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung.Pten regulates homeostasis and inflammation-induced migration of myelocytes in zebrafishMyeloid PTEN deficiency protects livers from ischemia reperfusion injury by facilitating M2 macrophage differentiation.The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia.Disruption of Pten speeds onset and increases severity of spontaneous colitis in Il10(-/-) miceBlockade of the PI-3K signalling pathway by the Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces macrophages to synthesize and secrete pro-inflammatory cytokinesRestoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis.Insulin hypersensitivity induced by hepatic PTEN gene ablation protects from murine endotoxemia.PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase.PTEN-Foxo1 signaling triggers HMGB1-mediated innate immune responses in acute lung injuryGlucocorticoid-Augmented Efferocytosis Inhibits Pulmonary Pneumococcal Clearance in Mice by Reducing Alveolar Macrophage Bactericidal Function.Phosphatase PTEN is critically involved in post-myocardial infarction remodeling through the Akt/interleukin-10 signaling pathway.PTEN directly activates the actin depolymerization factor cofilin-1 during PGE2-mediated inhibition of phagocytosis of fungiSustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways.Delayed administration of a PTEN inhibitor BPV improves functional recovery after experimental strokeMyeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition.L-plastin is essential for alveolar macrophage production and control of pulmonary pneumococcal infectionPneumococcal pneumonia: mechanisms of infection and resolution.Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3KMolecular control of PtdIns(3,4,5)P3 signaling in neutrophils.Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases.PI3K inhibitors in inflammation, autoimmunity and cancer.Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR.The functions of tumor suppressor PTEN in innate and adaptive immunity.Myeloid cell-specific inositol polyphosphate-4-phosphatase type I knockout mice impair bacteria clearance in a murine peritonitis model.Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia.Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses.Postischemic administration of a potent PTEN inhibitor reduces spontaneous lung infection following experimental stroke.Myeloid Notch1 Deficiency Activates RhoA/ROCK Pathway and Aggravates Hepatocellular Damage In Mouse Ischemic Livers.Phosphatase and tensin homolog-β-catenin signaling modulates regulatory T cells and inflammatory responses in mouse liver ischemia/reperfusion injury.Anti-inflammatory properties of the PI3K pathway are mediated by IL-10/DUSP regulation.Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity.Monitoring neutrophils and platelets during casein-induced anaphylaxis in an experimental BALB/c mouse model.MicroRNA 21 in tissue injury and inflammation.
P2860
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P2860
Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
@zh-hant
name
Myeloid PTEN promotes inflamma ...... murine pneumococcal pneumonia.
@en
Myeloid PTEN promotes inflamma ...... murine pneumococcal pneumonia.
@nl
type
label
Myeloid PTEN promotes inflamma ...... murine pneumococcal pneumonia.
@en
Myeloid PTEN promotes inflamma ...... murine pneumococcal pneumonia.
@nl
prefLabel
Myeloid PTEN promotes inflamma ...... murine pneumococcal pneumonia.
@en
Myeloid PTEN promotes inflamma ...... murine pneumococcal pneumonia.
@nl
P2093
P50
P356
P1476
Myeloid PTEN promotes inflamma ...... murine pneumococcal pneumonia.
@en
P2093
Bernd R Binder
Bianca Doninger
Ildiko Mesteri
Immanuel Elbau
Joanna Warszawska
Philipp Günzl
Tanja Furtner
P304
P356
10.4049/JIMMUNOL.0902221
P407
P577
2010-05-26T00:00:00Z