The transcription factor Sox2 is required for osteoblast self-renewal.
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Roles of FGF signaling in stem cell self-renewal, senescence and agingGenetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of boneVascular calcification and aortic fibrosis: a bifunctional role for osteopontin in diabetic arteriosclerosisBRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model.Spontaneous and therapy-induced immunity to pluripotency genes in humans: clinical implications, opportunities and challenges.SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells.Intercellular adhesion molecule-1 inhibits osteogenic differentiation of mesenchymal stem cells and impairs bio-scaffold-mediated bone regeneration in vivo.The Sox2 high mobility group transcription factor inhibits mature osteoblast function in transgenic miceSox2 antagonizes the Hippo pathway to maintain stemness in cancer cellsSOX2 has a crucial role in the lineage determination and proliferation of mesenchymal stem cells through Dickkopf-1 and c-MYC.FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2.Over-expression of Sox2 in C3H10T1/2 cells inhibits osteoblast differentiation through Wnt and MAPK signalling pathways.Osteosarcoma cell proliferation and survival requires mGluR5 receptor activity and is blocked by Riluzole.Embryonic stem cells and inducible pluripotent stem cells: two faces of the same coin?SOX2 regulates YAP1 to maintain stemness and determine cell fate in the osteo-adipo lineage.PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity.Human trabecular meshwork cells exhibit several characteristics of, but are distinct from, adipose-derived mesenchymal stem cells.FGF/FGFR signaling in bone formation: progress and perspectives.The SOX family of genes in cancer development: biological relevance and opportunities for therapy.The sox family of transcription factors: versatile regulators of stem and progenitor cell fate.Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.miR-34a is downregulated in human osteosarcoma stem-like cells and promotes invasion, tumorigenic ability and self-renewal capacityAn isolated cryptic peptide influences osteogenesis and bone remodeling in an adult mammalian model of digit amputation.Sox2 maintains self renewal of tumor-initiating cells in osteosarcomasPartial characterization of the Sox2+ cell population in an adult murine model of digit amputation.Potential role of S-adenosylmethionine in osteosarcoma development.Sox2 contributes to tooth development via Wnt signaling.SIRT1 directly regulates SOX2 to maintain self-renewal and multipotency in bone marrow-derived mesenchymal stem cells.Low Oxygen Modulates Multiple Signaling Pathways, Increasing Self-Renewal, While Decreasing Differentiation, Senescence, and Apoptosis in Stromal MIAMI Cells.Expression of OCT-4 and SOX-2 in Bone Marrow-Derived Human Mesenchymal Stem Cells during Osteogenic DifferentiationImportance of Sox2 in maintenance of cell proliferation and multipotency of mesenchymal stem cells in low-density culture.Human Periosteal Derived Stem Cell Potential: The Impact of age.Morphological and molecular changes of human granulosa cells exposed to 5-azacytidine and addressed toward muscular differentiation.Characterization and differentiation potential of rabbit mesenchymal stem cells for translational regenerative medicine.Sox2 is dispensable for primary melanoma and metastasis formation.Influence of Micropatterning on Human Periodontal Ligament Cells' Behavior.Subchondral bone derived mesenchymal stem cells display enhanced osteo-chondrogenic differentiation, self-renewal and proliferation potentials.YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling.
P2860
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P2860
The transcription factor Sox2 is required for osteoblast self-renewal.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
The transcription factor Sox2 is required for osteoblast self-renewal.
@en
The transcription factor Sox2 is required for osteoblast self-renewal.
@nl
type
label
The transcription factor Sox2 is required for osteoblast self-renewal.
@en
The transcription factor Sox2 is required for osteoblast self-renewal.
@nl
prefLabel
The transcription factor Sox2 is required for osteoblast self-renewal.
@en
The transcription factor Sox2 is required for osteoblast self-renewal.
@nl
P2093
P2860
P356
P1476
The transcription factor Sox2 is required for osteoblast self-renewal.
@en
P2093
C Basilico
D Ambrosetti
S K Nicolis
U Basu-Roy
P2860
P2888
P304
P356
10.1038/CDD.2010.57
P577
2010-05-21T00:00:00Z
P5875
P6179
1007508633