Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.
about
A common 5'-UTR variant in MATE2-K is associated with poor response to metformin.Molecular determinants of ligand selectivity for the human multidrug and toxin extruder proteins MATE1 and MATE2-K.Drug discovery using clinical outcome-based Connectivity Mapping: application to ovarian cancerTwelve transmembrane helices form the functional core of mammalian MATE1 (multidrug and toxin extruder 1) proteinRole of ABC and Solute Carrier Transporters in the Placental Transport of Lamivudine.Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomicsTransporter-mediated drug-drug interactions.Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics.Multidrug and toxin extrusion proteins as transporters of antimicrobial drugs.Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.Renal transport of organic anions and cations.A Comprehensive Review of Drug-Drug Interactions with Metformin.Structure and function of multidrug and toxin extrusion proteins (MATEs) and their relevance to drug therapy and personalized medicine.Investigation of endogenous compounds for assessing the drug interactions in the urinary excretion involving multidrug and toxin extrusion proteins.Renal Drug Transporters and Drug Interactions.Pharmacokinetics of Immediate and Sustained Release Cephalexin Administered by Different Routes to Llamas (Lama glama)The involvement of multidrug and toxin extrusion protein 1 in the distribution and excretion of berberine.Impact of Experimental Conditions on the Evaluation of Interactions between Multidrug and Toxin Extrusion Proteins and Candidate Drugs.Solute Carrier (SLC) Family Transporters
P2860
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P2860
Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.
@en
Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.
@nl
type
label
Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.
@en
Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.
@nl
prefLabel
Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.
@en
Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.
@nl
P2093
P356
P1476
Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice.
@en
P2093
Ken-Ichi Inui
Masahiro Tsuda
Shingo Watanabe
Tomohiro Terada
Toshiya Katsura
P304
P356
10.1124/JPET.110.169433
P407
P577
2010-05-19T00:00:00Z