Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU
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The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundaryG4 resolvase 1 tightly binds and unwinds unimolecular G4-DNARNA helicases at work: binding and rearrangingRNA Secondary Structure Modulates FMRP's Bi-Functional Role in the MicroRNA PathwayG-quadruplexes and helicasesG-quadruplexes and their regulatory roles in biologyRNA helicase proteins as chaperones and remodelersRNA helicases in infection and disease.Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAsA G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1.The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1.DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formationInsights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase.Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNAThe DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzymeBiophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU.Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide-quadruplex complexG4-associated human diseases.A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation.Role of conserved cis-regulatory elements in the post-transcriptional regulation of the human MECP2 gene involved in autism.Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU).RHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis.G-quadruplexes: targets and tools in anticancer drug design.Telomere lengthening and other functions of telomerase.The tale of RNA G-quadruplex.RNA Helicase Associated with AU-rich Element (RHAU/DHX36) Interacts with the 3'-Tail of the Long Non-coding RNA BC200 (BCYRN1).RNA G-quadruplexes: emerging mechanisms in diseaseAven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes.Targeting Translation Initiation Bypasses Signaling Crosstalk Mechanisms That Maintain High MYC Levels in Colorectal Cancer.Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.RNA G-quadruplexes and their potential regulatory roles in translation.RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms.The 5' guanosine tracts of human telomerase RNA are recognized by the G-quadruplex binding domain of the RNA helicase DHX36 and function to increase RNA accumulation.Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region.QGRS-H Predictor: a web server for predicting homologous quadruplex forming G-rich sequence motifs in nucleotide sequences.DExD/H-Box Helicase 36 Signaling via Myeloid Differentiation Primary Response Gene 88 Contributes to NF-κB Activation to Type 2 Porcine Reproductive and Respiratory Syndrome Virus Infection.On Characterizing the Interactions between Proteins and Guanine Quadruplex Structures of Nucleic Acids.RNA G-quadruplex secondary structure promotes alternative splicing via the RNA-binding protein hnRNPF.Structure and function of Pif1 helicase.The G-quadruplex (G4) resolvase DHX36 efficiently and specifically disrupts DNA G4s via a translocation-based helicase mechanism.
P2860
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P2860
Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
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name
Role of the amino terminal RHA ...... the DEAH-box RNA helicase RHAU
@en
Role of the amino terminal RHA ...... he DEAH-box RNA helicase RHAU.
@nl
type
label
Role of the amino terminal RHA ...... the DEAH-box RNA helicase RHAU
@en
Role of the amino terminal RHA ...... he DEAH-box RNA helicase RHAU.
@nl
prefLabel
Role of the amino terminal RHA ...... the DEAH-box RNA helicase RHAU
@en
Role of the amino terminal RHA ...... he DEAH-box RNA helicase RHAU.
@nl
P2093
P2860
P356
P1476
Role of the amino terminal RHA ...... the DEAH-box RNA helicase RHAU
@en
P2093
Banabihari Giri
James P Vaughn
Simon Lattmann
Steven A Akman
Yoshikuni Nagamine
P2860
P304
P356
10.1093/NAR/GKQ372
P407
P577
2010-05-14T00:00:00Z