The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription. - Wikidata - awgldk - TriplyDB

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

http://www.wikidata.org/entity/Q39705131

about

Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling The pre-B cell receptor; selecting for or against autoreactivity Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.The pre-B cell receptor checkpoint.DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3 Interferon regulatory factors 4 and 8 induce the expression of Ikaros and Aiolos to down-regulate pre-B-cell receptor and promote cell-cycle withdrawal in pre-B-cell development Combined immunofluorescence and DNA FISH on 3D-preserved interphase nuclei to study changes in 3D nuclear organization.Tolerance checkpoints in B-cell development: Johnny B good.Mechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia.Checkpoints that control B cell development.A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosome-associated protein transmembrane 5.The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development.The epigenetic profile of Ig genes is dynamically regulated during B cell differentiation and is modulated by pre-B cell receptor signaling Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival.Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis.Transcription of productive and nonproductive VDJ-recombined alleles after IgH allelic exclusion.The BTG2-PRMT1 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex.

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The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

http://www.wikidata.org/entity/Q39705131

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

@en

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

@nl

type

label

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

@en

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

@nl

prefLabel

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

@en

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

@nl

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SJ.EMBOJ.7600850

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The EMBO Journal

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The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription

@en

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Geoff Morgan

http://www.w3.org/2001/XMLSchema#string

Hassan Jumaa

http://www.w3.org/2001/XMLSchema#string

Lena Erlandsson

http://www.w3.org/2001/XMLSchema#string

Lyubomira Chakalova

http://www.w3.org/2001/XMLSchema#string

Mathew J Parker

http://www.w3.org/2001/XMLSchema#string

Steve Licence

http://www.w3.org/2001/XMLSchema#string

Thomas H Winkler

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Translating the Histone Code

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene

The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface

Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell development

The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain

Review article: role of the surrogate light chain and the pre-B-cell receptor in mouse B-cell development.

A second gene, VpreB in the lambda 5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes.

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3895-3905

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scholarly article

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10.1038/SJ.EMBOJ.7600850

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22

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24

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Cameron S. Osborne

Inga-Lill Martensson

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2005-11-10T00:00:00Z

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7487297

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16281060

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1283949

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