The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene
about
Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activitiesCell cycle-specific function of Ikaros in human leukemiaRepression by Ikaros and Aiolos is mediated through histone deacetylase complexesZinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte developmentHelios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatinRole of Ikaros in T-cell acute lymphoblastic leukemiaIkaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activityEos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous systemIkaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repressionUnconventional potentiation of gene expression by IkarosA molecular dissection of the repression circuitry of IkarosDown-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activatorThe murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell developmentRepression of myelin proteolipid protein gene expression is mediated through both general and cell type-specific negative regulatory elements in nonexpressing cellsMutations of the Drosophila zinc finger-encoding gene vielfältig impair mitotic cell divisions and cause improper chromosome segregation.Conservation of a master hematopoietic switch gene during vertebrate evolution: isolation and characterization of Ikaros from teleost and amphibian species.From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitmentCharacterization of the B lymphocyte-induced maturation protein-1 (Blimp-1) gene, mRNA isoforms and basal promoter.Review article: role of the surrogate light chain and the pre-B-cell receptor in mouse B-cell development.An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.Identification of human granzyme B promoter regulatory elements interacting with activated T-cell-specific proteins: implication of Ikaros and CBF binding sites in promoter activation.Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies.Restriction of IL-22-producing T cell responses and differential regulation of regulatory T cell compartments by zinc finger transcription factor IkarosIkaros, a lymphoid-cell-specific transcription factor, contributes to the leukemogenic phenotype of a mink cell focus-inducing murine leukemia virusMast cell IL-4 expression is regulated by Ikaros and influences encephalitogenic Th1 responses in EAEHaematopoietic cell-fate decisions, chromatin regulation and ikaros.Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes.Human hematopoietic lineage commitment.Dissecting teleost B cell differentiation using transcription factors.Regulator of myeloid differentiation and function: The secret life of Ikaros.Ikaros isoforms: The saga continues.Targeting of Ikaros to pericentromeric heterochromatin by direct DNA bindingMi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function.The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes.Biochemical and cellular characterization of transcription factors binding to the hyperconserved core promoter-associated M4 motif.Alternative splicing regulates Prdm1/Blimp-1 DNA binding activities and corepressor interactionsDefects in hemopoietic stem cell activity in Ikaros mutant mice.The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform.Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.
P2860
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P2860
The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene
description
1994 nî lūn-bûn
@nan
1994 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
The lymphoid transcription fac ...... s derived from the Ikaros gene
@ast
The lymphoid transcription fac ...... s derived from the Ikaros gene
@en
The lymphoid transcription fac ...... s derived from the Ikaros gene
@nl
type
label
The lymphoid transcription fac ...... s derived from the Ikaros gene
@ast
The lymphoid transcription fac ...... s derived from the Ikaros gene
@en
The lymphoid transcription fac ...... s derived from the Ikaros gene
@nl
prefLabel
The lymphoid transcription fac ...... s derived from the Ikaros gene
@ast
The lymphoid transcription fac ...... s derived from the Ikaros gene
@en
The lymphoid transcription fac ...... s derived from the Ikaros gene
@nl
P2093
P2860
P3181
P356
P1476
The lymphoid transcription fac ...... s derived from the Ikaros gene
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.14.11.7111
P407
P50
P577
1994-11-01T00:00:00Z